Rerouting DOT1L inhibitors in leukemia

被引:1
|
作者
Dickins, Ross A. [1 ]
机构
[1] Monash Univ, Clayton, Vic, Australia
关键词
D O I
10.1182/blood.2020007352
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this issue of Blood, Perner and colleagues show that 2 new DOT1L inhibitors with favorable administration routes and pharmacokinetic properties yield promising antileukemic activity in patient-derived xenograft (PDX) models of MLL-rearranged acute myeloid leukemia (AML).(1)
引用
收藏
页码:1990 / 1901
页数:3
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