Onychocytic Carcinoma: A New Entity

被引：21

作者：

Perrin, Christophe ^{[1
]}

Langbein, Lutz ^{[2
]}

Ambrossetti, Damien ^{[1
]}

Erfan, Nouran ^{[1
]}

Schweizer, Juergen ^{[2
]}

Michiels, Jean-Francois ^{[1
]}

机构：

[1] Univ Nice, Lab Cent Anat Pathol, Hop Pasteur, Nice, France

[2] German Canc Res Ctr, Div Genet Skin Carcinogenesis, Sect Normal & Neoplast Epidermal Differentiat, Heidelberg, Germany

来源：

AMERICAN JOURNAL OF DERMATOPATHOLOGY | 2013年 / 35卷 / 06期

关键词：

onychomatricoma; Bowen disease; onychocytic matricoma; nail; hair follicle; skin appendage neoplasm; hair keratins; pilomatrix carcinoma; BOWENS-DISEASE; NAIL UNIT; ONYCHOMATRICOMA; EXPRESSION; KERATINS; MATRIX; CELLS;

D O I：

10.1097/DAD.0b013e3182827fec

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We have recently described a new nail tumor known as onychocytic matricoma. Herein, we describe its malignant counterpart. Clinically, the tumor simulates onychomatricoma (OM). Histologically, this in situ malignant epithelial tumor exhibits a distinct picture of onychocytic differentiation with signs of both nail matrical differentiation and nail plate differentiation. We have proposed the name onychocytic carcinoma for this singular adnexal neoplasm. Given the peculiar thickening of the nail plate observed in OM, onychocytic matricoma, and onychocytic carcinoma, the clinical individualization of a new type of nail band pattern could be proposed. It presents as an acquired localized (monodactylous) longitudinal pachyonychia. Such longitudinal pachyonychia allow the recognition of the matrical nail tumor, which has a limited etiological spectrum. Xantholeucopachyonychia suggests mainly OM and rarely onychocytic carcinoma. Pachymelanonychia suggests onychocytic matricoma and rarely pigmented OM or onychocytic carcinoma.

引用

页码：679 / 684

页数：6

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