Hydrophobic ionic liquids-assisted polymer recovery during penicillin extraction in aqueous two-phase system

被引：72
|
作者：
Jiang, Yangyang [2 ]
Xia, Hansong [2 ]
Yu, Jiang [1 ]
Guo, Chen [2 ]
Liu, Huizhou [2 ]
机构：
[1] Beijing Univ Chem Technol, Beijing, Peoples R China
[2] Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Lab Separat Sci & Engn, Beijing 100080, Peoples R China
来源：
CHEMICAL ENGINEERING JOURNAL | 2009年 / 147卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Ionic liquids; Aqueous two-phase; Extraction separation; Penicillin; PEG; PURIFICATION; PARTITION; EFFICIENT; SALT;
D O I：
10.1016/j.cej.2008.11.012
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
In this study, terminal modified poly(ethylene glycerol) (PEG) was employed as the phase-forming polymer to construct aqueous two-phase (ATP). After the phase equilibrium, 95.8% penicillin could be extracted into imidazole-terminal PEG-rich phase efficiently. Imidazole-terminal PEG (I-PEG) was separated from the aqueous phase containing penicillin to hydrophobic ionic liquid phase at basic pH, and a weak acidic aqueous phase was then employed to recover the I-PEG from the hydrophobic ionic liquid phase into water at pH 5.5-6. The recycle of the polymer was achieved with the aid of hydrophobic ionic liquids. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码：22 / 26
页数：5
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