Lymphocyte infusion for delayed extramedullary relapse of acute leukemia following bone marrow transplantation

被引:15
|
作者
Fleming, DR
Greenwood, MF
Garrison, J
Geil, JD
Romond, EH
机构
[1] Markey Cancer Center, Department of Medicine, University of Kentucky Markey Cancer Center, Lexington, KY
[2] Department of Pediatrics, Divisions of Hematology/Oncology, University of Kentucky Markey Cancer Center, Lexington, KY
[3] Department of Medicine, Division of Hematology/Oncology, University of Kentucky, Markey Cancer Center, Lexington, KY 40536-0093
关键词
acute myelogenous leukemia; donor lymphocyte infusion; extramedullary; relapse; allogeneic bone marrow transplantation;
D O I
10.3109/10428199609093456
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We report a case of extramedullary relapse of acute myelogenous leukemia twelve years after allogeneic bone marrow transplantation. Due to the localized nature of the relapse, we were able to eliminate a majority of the tumor burden, utilizing local irradiation. Destined with eventual systemic leukemia relapse, further therapy utilizing donor lymphocytes was given at a time of minimal disease burden. The patient remains in a state of complete remission.
引用
收藏
页码:525 / 528
页数:4
相关论文
共 50 条
  • [21] Membranous nephropathy associated with donor lymphocyte infusion following allogeneic bone marrow transplantation
    Miyazaki, Y
    Mori, Y
    Kishimoto, N
    Matsumoto, N
    Zen, K
    Amakawa, R
    Kishimoto, Y
    Fukuhara, S
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2003, 78 (03) : 262 - 265
  • [22] Factors affecting survival in acute leukemia with donor lymphocyte infusion in the first relapse after allogeneic stem cell transplantation
    Kurnaz, Fatih
    Sahin, Cem
    Kaynar, Leylagul
    Pala, Cigdem
    Sivgin, Serdar
    Altuntas, Fevzi
    Eser, Bulent
    Cetin, Mustafa
    Unal, Ali
    JOURNAL OF BUON, 2016, 21 (01): : 227 - 234
  • [23] Thalidomide is effective for extramedullary relapse of multiple myeloma postallogeneic bone marrow transplantation
    Biagi, JJ
    Prince, HM
    BRITISH JOURNAL OF HAEMATOLOGY, 2001, 115 (02) : 484 - 485
  • [24] Isolated Extramedullary Relapse of Acute Leukemia after Allogeneic Stem Cell Transplantation: Different Kinetics and Better Prognosis than Systemic Relapse
    Shem-Tov, Noga
    Saraceni, Francesco
    Danylesko, Ivetta
    Shouval, Roni
    Yerushalmi, Ronit
    Nagler, Arnon
    Shimoni, Avichai
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2017, 23 (07) : 1087 - 1094
  • [25] Donor lymphocyte infusion as therapy for pure red cell aplasia following bone marrow transplantation
    Bavaro, P
    Di Girolamo, G
    Olioso, P
    Papalinetti, G
    Iacone, A
    Accorsi, P
    Di Bartolomeo, P
    BRITISH JOURNAL OF HAEMATOLOGY, 1999, 104 (04) : 930 - 931
  • [26] Treatment of relapsed acute myeloid leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: a high incidence of isolated extramedullary relapse
    S-J Choi
    J-H Lee
    J-H Lee
    S Kim
    M Seol
    Y-S Lee
    J-S Lee
    W-K Kim
    H-S Chi
    K-H Lee
    Leukemia, 2004, 18 : 1789 - 1797
  • [27] Donor lymphocyte infusion for childhood acute lymphoblastic leukaemia relapsing after bone marrow transplantation
    Atra, A
    Millar, B
    Shepherd, V
    Shankar, A
    Wilson, K
    Treleaven, J
    PritchardJones, K
    Meller, ST
    Pinkerton, CR
    BRITISH JOURNAL OF HAEMATOLOGY, 1997, 97 (01) : 165 - 168
  • [28] Treatment of relapsed acute myeloid leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: a high incidence of isolated extramedullary relapse
    Choi, SJ
    Lee, JH
    Lee, JH
    Kim, S
    Seol, M
    Lee, YS
    Lee, JS
    Kim, WK
    Chi, HS
    Lee, KH
    LEUKEMIA, 2004, 18 (11) : 1789 - 1797
  • [29] Role of radiotherapy in treatment of extramedullary relapse following total marrow and lymphoid irradiation in high-risk and/or relapsed/refractory acute leukemia
    Ladbury, Colton
    Semwal, Hemal
    Hong, Daniel
    Yang, Dongyun
    Hao, Claire
    Han, Chunhui
    Liu, An
    Marcucci, Guido
    Rosenthal, Joseph
    Hui, Susanta
    Salhotra, Amandeep
    Ali, Haris
    Nakamura, Ryotaro
    Stein, Anthony
    Al Malki, Monzr
    Wong, Jeffrey Y. C.
    Dandapani, Savita
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [30] Donor lymphocyte infusion for leukemia relapse after hematopoietic stem cell transplantation
    Yegin, Zeynep Arzu
    Ozkurt, Zuebeyde Nur
    Aki, Sahika Zeynep
    Sucak, Guelsan Tuerkoez
    TRANSFUSION AND APHERESIS SCIENCE, 2010, 42 (03) : 239 - 245