Lymphocyte infusion for delayed extramedullary relapse of acute leukemia following bone marrow transplantation

被引:15
|
作者
Fleming, DR
Greenwood, MF
Garrison, J
Geil, JD
Romond, EH
机构
[1] Markey Cancer Center, Department of Medicine, University of Kentucky Markey Cancer Center, Lexington, KY
[2] Department of Pediatrics, Divisions of Hematology/Oncology, University of Kentucky Markey Cancer Center, Lexington, KY
[3] Department of Medicine, Division of Hematology/Oncology, University of Kentucky, Markey Cancer Center, Lexington, KY 40536-0093
关键词
acute myelogenous leukemia; donor lymphocyte infusion; extramedullary; relapse; allogeneic bone marrow transplantation;
D O I
10.3109/10428199609093456
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We report a case of extramedullary relapse of acute myelogenous leukemia twelve years after allogeneic bone marrow transplantation. Due to the localized nature of the relapse, we were able to eliminate a majority of the tumor burden, utilizing local irradiation. Destined with eventual systemic leukemia relapse, further therapy utilizing donor lymphocytes was given at a time of minimal disease burden. The patient remains in a state of complete remission.
引用
收藏
页码:525 / 528
页数:4
相关论文
共 50 条
  • [11] Extramedullary relapse after allogeneic bone marrow transplantation for haematological malignancy
    G Chong
    G Byrnes
    J Szer
    A Grigg
    Bone Marrow Transplantation, 2000, 26 : 1011 - 1015
  • [12] Extramedullary relapse after allogeneic bone marrow transplantation for haematological malignancy
    Chong, G
    Byrnes, G
    Szer, J
    Grigg, A
    BONE MARROW TRANSPLANTATION, 2000, 26 (09) : 1011 - 1015
  • [13] Isolated extra-medullary relapse of acute leukemia following allogeneic bone marrow transplantation
    Firas, Al Sabty
    Demeckova, E.
    Bojtarova, E.
    Czako, B.
    Hrubisko, M.
    Mistrik, M.
    BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, 2008, 109 (08): : 358 - 361
  • [14] Lymphocyte recovery after allogeneic bone marrow transplantation predicts risk of relapse in acute lymphoblastic leukemia
    S Kumar
    M G Chen
    D A Gastineau
    M A Gertz
    D J Inwards
    M Q Lacy
    A Tefferi
    M R Litzow
    Leukemia, 2003, 17 : 1865 - 1870
  • [15] Isolated extramedullary relapse of acute lymphoblastic leukaemia after allogeneic bone marrow transplantation
    WY Au
    AKW Lie
    R Liang
    YL Kwong
    Bone Marrow Transplantation, 1999, 24 : 1137 - 1140
  • [16] Isolated extramedullary relapse of acute lymphoblastic leukaemia after allogeneic bone marrow transplantation
    Au, WY
    Lie, AKW
    Liang, R
    Kwong, YL
    BONE MARROW TRANSPLANTATION, 1999, 24 (10) : 1137 - 1140
  • [17] Donor lymphocyte infusion induced molecular remission in relapse of acute myeloid leukaemia after allogeneic bone marrow transplantation
    WY Au
    AKW Lie
    CK Lee
    R Liang
    YL Kwong
    Bone Marrow Transplantation, 1999, 23 : 1201 - 1203
  • [18] Donor lymphocyte infusion induced molecular remission in relapse of acute myeloid leukaemia after allogeneic bone marrow transplantation
    Au, WY
    Lie, AKW
    Lee, CK
    Liang, R
    Kwong, YL
    BONE MARROW TRANSPLANTATION, 1999, 23 (11) : 1201 - 1203
  • [19] Repeated Relapses of Acute Myelogenous Leukemia in the Isolated Extramedullary Sites Following Allogeneic Bone Marrow Transplantations
    Kikushige, Yoshikane
    Takase, Ken
    Sata, Keiko
    Aoki, Ken-ichi
    Numata, Akihiko
    Miyamoto, Toshihiro
    Fukuda, Takahiro
    Gondo, Hisashi
    Harada, Mine
    Nagafuji, Koji
    INTERNAL MEDICINE, 2007, 46 (13) : 1011 - 1014
  • [20] Membranous Nephropathy Associated with Donor Lymphocyte Infusion following Allogeneic Bone Marrow Transplantation
    Yasuhiko Miyazaki
    Yasukiyo Mori
    Noriko Kishimoto
    Noriaki Matsumoto
    Katsuhiro Zen
    Ryuichi Amakawa
    Yuji Kishimoto
    Shirou Fukuhara
    International Journal of Hematology, 2003, 78 : 262 - 265