Synthesis of N1,N3-disubstituted formamidrazones via the TMSCl-promoted reaction of isocyanides with thiosemicarbazones

被引：2

作者：

Sarnpitak, Pakornwit ^{[1
]}

Tsirulnikov, Sergey ^{[2
]}

Krasavin, Mikhail ^{[1
]}

机构：

[1] Griffith Univ, Eskitis Inst Cell & Mol Therapies, Nathan, Qld 4111, Australia

[2] Yaroslavl State Pedag Univ, Sci & Educ Ctr Innovat Res, Yaroslavl 150000, Russia

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 48期

关键词：

Isocyanide-based multicomponent reactions; Isocyanide insertion; Lewis acid catalysis; Chlorotrimethylsilane; Formamidrazones; MULTICOMPONENT REACTIONS; CARBONYL;

D O I：

10.1016/j.tetlet.2012.09.085

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A hitherto undescribed TMSCl-promoted reaction of thiosemicarbazones was found to give rare N-1,N-3-disubstituted formamidrazones in fair to excellent yields. The scope of this new reaction was investigated and a plausible mechanism proposed. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：6540 / 6543

页数：4

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