Synthesis of N1,N3-disubstituted formamidrazones via the TMSCl-promoted reaction of isocyanides with thiosemicarbazones

被引：2
|
作者：
Sarnpitak, Pakornwit [1 ]
Tsirulnikov, Sergey [2 ]
Krasavin, Mikhail [1 ]
机构：
[1] Griffith Univ, Eskitis Inst Cell & Mol Therapies, Nathan, Qld 4111, Australia
[2] Yaroslavl State Pedag Univ, Sci & Educ Ctr Innovat Res, Yaroslavl 150000, Russia
来源：
TETRAHEDRON LETTERS | 2012年 / 53卷 / 48期
关键词：
Isocyanide-based multicomponent reactions; Isocyanide insertion; Lewis acid catalysis; Chlorotrimethylsilane; Formamidrazones; MULTICOMPONENT REACTIONS; CARBONYL;
D O I：
10.1016/j.tetlet.2012.09.085
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A hitherto undescribed TMSCl-promoted reaction of thiosemicarbazones was found to give rare N-1,N-3-disubstituted formamidrazones in fair to excellent yields. The scope of this new reaction was investigated and a plausible mechanism proposed. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：6540 / 6543
页数：4
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