Flow photochemistry: Old light through new windows

被引:346
作者
Knowles, Jonathan P. [1 ]
Elliott, Luke D. [1 ]
Booker-Milburn, Kevin I. [1 ]
机构
[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England
关键词
cycloaddition; flow chemistry; photocatalysis; photochemistry; photooxygenation; DIASTEREOSELECTIVE 2+2 PHOTOCYCLOADDITION; SINGLET-OXYGEN; PHOTOSENSITIZED ADDITION; MULTISTEP SYNTHESIS; PHOTODECARBOXYLATIVE ADDITIONS; PHOTOCATALYTIC OXIDATION; N-ALKYLATION; AMINO-ACIDS; MICROREACTOR; GENERATION;
D O I
10.3762/bjoc.8.229
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Synthetic photochemistry carried out in classic batch reactors has, for over half a century, proved to be a powerful but under-utilised technique in general organic synthesis. Recent developments in flow photochemistry have the potential to allow this technique to be applied in a more mainstream setting. This review highlights the use of flow reactors in organic photochemistry, allowing a comparison of the various reactor types to be made.
引用
收藏
页码:2025 / 2052
页数:28
相关论文
共 105 条
[1]   A practical synthesis of a [2.2.1] bicyclic chiral sulfide for asymmetric transformations [J].
Aggarwal, Varinder K. ;
Fang, Guangyu ;
Kokotos, Christoforos G. ;
Richardson, Jeffery ;
Unthank, Matthew G. .
TETRAHEDRON, 2006, 62 (49) :11297-11303
[2]   THE PHOTOCHEMISTRY OF THE N-OXIDE FUNCTION [J].
ALBINI, A ;
ALPEGIANI, M .
CHEMICAL REVIEWS, 1984, 84 (01) :43-71
[3]   Development of an Improved Process for Doxercalciferol via a Continuous Photochemical Reaction [J].
Anderson, Bruce G. ;
Bauta, William E. ;
Cantrell, William R., Jr. .
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2012, 16 (05) :967-975
[4]   A Photoflow Reactor for the Continuous Photoredox-Mediated Synthesis of C-Glycoamino Acids and C-Glycolipids [J].
Andrews, R. Stephen ;
Becker, Jennifer J. ;
Gagne, Michel R. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (17) :4140-4143
[5]   Porous Photocatalytic Membrane Microreactor (P2M2): A new reactor concept for photochemistry [J].
Aran, H. C. ;
Salamon, D. ;
Rijnaarts, T. ;
Mul, G. ;
Wessling, M. ;
Lammertink, R. G. H. .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2011, 225 (01) :36-41
[6]   Enantioselective radical cyclisation reactions of 4-substituted quinolones mediated by a chiral template [J].
Bakowski, Aline ;
Dressel, Martina ;
Bauer, Andreas ;
Bach, Thorsten .
ORGANIC & BIOMOLECULAR CHEMISTRY, 2011, 9 (09) :3516-3529
[7]   A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly [J].
Baxendale, Ian R. ;
Deeley, Jon ;
Griffiths-Jones, Charlotte M. ;
Ley, Steven V. ;
Saaby, Steen ;
Tranmer, Geoffrey K. .
CHEMICAL COMMUNICATIONS, 2006, (24) :2566-2568
[8]   Multi-Step Synthesis by Using Modular Flow Reactors: The Preparation of Yne-Ones and Their Use in Heterocycle Synthesis [J].
Baxendale, Ian R. ;
Schou, Soren C. ;
Sedelmeier, Joerg ;
Ley, Steven V. .
CHEMISTRY-A EUROPEAN JOURNAL, 2010, 16 (01) :89-94
[9]   Multistep Synthesis Using Modular Flow Reactors: Bestmann-Ohira Reagent for the Formation of Alkynes and Triazoles [J].
Baxendale, Ian R. ;
Ley, Steven V. ;
Mansfield, Andrew C. ;
Smith, Christopher D. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (22) :4017-4021
[10]   Photodecarboxylative benzylations of phthalimide in pH 7 buffer: a simple access to 3-arylmethyleneisoindolin-1-ones [J].
Belluau, Vincent ;
Noeureuil, Pierre ;
Ratzke, Elfrun ;
Skvortsov, Aleksei ;
Gallagher, Sonia ;
Motti, Cherri Ann ;
Oelgemoeller, Michael .
TETRAHEDRON LETTERS, 2010, 51 (36) :4738-4741