The effect of pimecrolimus on innate immunity in subjects with atopic dermatitis: a double-blind, randomized, vehicle-controlled study

被引：6

作者：

Afshar, M. ^{[1
]}

Kotol, P. ^{[1
]}

Miller, J. ^{[1
]}

Gallo, R. ^{[1
]}

Hata, T. ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Med, Div Dermatol, San Diego, CA 92122 USA

来源：

BRITISH JOURNAL OF DERMATOLOGY | 2013年 / 168卷 / 02期

关键词：

ANTIMICROBIAL PEPTIDES; EXPRESSION; INFECTIONS;

D O I：

10.1111/j.1365-2133.2012.11052.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

引用

页码：426 / 428

页数：3

共 10 条

[1] Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice [J].

Aberg, Karin M. ;

Radek, Katherine A. ;

Choi, Eung-Ho ;

Kim, Dong-Kun ;

Demerjian, Marianne ;

Hupe, Melanie ;

Kerbleski, Joseph ;

Gallo, Richard L. ;

Ganz, Tomas ;

Mauro, Theodora ;

Feingold, Kenneth R. ;

Elias, Peter M. .

JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (11) :3339-3349

[2] Pimecrolimus Enhances TLR2/6-Induced Expression of Antimicrobial Peptides in Keratinocytes [J].

Buechau, Amanda S. ;

Schauber, Juergen ;

Hultsch, Thomas ;

Stuetz, Anton ;

Gallo, Richard L. .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2008, 128 (11) :2646-2654

[3] Pimecrolimus: A review [J].

Gupta, AK ;

Chow, M .

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2003, 17 (05) :493-503

[4] Enhanced Expression and Secretion of Antimicrobial Peptides in Atopic Dermatitis and after Superficial Skin Injury [J].

Harder, Juergen ;

Dressel, Stefanie ;

Wittersheim, Maike ;

Cordes, Jesko ;

Meyer-Hoffert, Ulf ;

Mrowietz, Ulrich ;

Foelster-Holst, Regina ;

Proksch, Ehrhard ;

Schroeder, Jens-Michael ;

Schwarz, Thomas ;

Glaeser, Regine .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2010, 130 (05) :1355-1364

[5] Differential suppression of epidermal antimicrobial protein expression in atopic dermatitis and in EFAD mice by pimecrolimus compared to corticosteroids [J].

Jensen, Jens-Michael ;

Ahrens, Kerstin ;

Meingassner, Josef ;

Scherer, Andreas ;

Braeutigam, Matthias ;

Stuetz, Anton ;

Schwarz, Thomas ;

Foelster-Holst, Regina ;

Harder, Juergen ;

Glaeser, Regine ;

Proksch, Ehrhardt .

EXPERIMENTAL DERMATOLOGY, 2011, 20 (10) :783-788

[6] Infection in atopic dermatitis [J].

Leung, DYM .

CURRENT OPINION IN PEDIATRICS, 2003, 15 (04) :399-404

[7]

Morsi HM, 2005, EGYPTIAN DERMATOL ON, V1, P1

[8] Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes [J].

Nomura, I ;

Goleva, E ;

Howell, MD ;

Hamid, QA ;

Ong, PY ;

Hall, CF ;

Darst, MA ;

Gao, BF ;

Boguniewicz, M ;

Travers, JB ;

Leung, DYM .

JOURNAL OF IMMUNOLOGY, 2003, 171 (06) :3262-3269

[9] Endogenous antimicrobial peptides and skin infections in atopic dermatitis [J].

Ong, PY ;

Ohtake, T ;

Brandt, C ;

Strickland, I ;

Boguniewicz, M ;

Ganz, T ;

Gallo, RL ;

Leung, DYM .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (15) :1151-1160

[10] Inflammatory cell numbers and cytokine expression in atopic dermatitis after topical pimecrolimus treatment [J].

Simon, D ;

Vassina, E ;

Yousefi, S ;

Braathen, LR ;

Simon, HU .

ALLERGY, 2005, 60 (07) :944-951

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