Molecular basis for adaptive responses during chemically induced hepatotoxicity

被引:6
作者
Burcham, PC [1 ]
机构
[1] Univ Western Australia, Queen Elizabeth II Med Ctr, Sch Med & Pharmacol, Pharmacol Unit, Nedlands, WA 6009, Australia
关键词
D O I
10.1093/toxsci/kfj059
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
[No abstract available]
引用
收藏
页码:349 / 351
页数:3
相关论文
共 18 条
[1]   Differential expression of mouse hepatic transporter genes in response to acetaminophen and carbon tetrachloride [J].
Aleksunes, LM ;
Slitt, AM ;
Cherrington, NJ ;
Thibodeau, MS ;
Klaassen, CD ;
Manautou, JE .
TOXICOLOGICAL SCIENCES, 2005, 83 (01) :44-52
[2]   PLASMA BILE-ACID ELEVATION FOLLOWING CCL-4 INDUCED LIVER-DAMAGE IN DOGS, SHEEP, CALVES AND PONIES [J].
ANWER, MS ;
ENGELKING, LR ;
GRONWALL, R ;
KLENTZ, RD .
RESEARCH IN VETERINARY SCIENCE, 1976, 20 (02) :127-130
[3]   Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice [J].
Assem, M ;
Schuetz, EG ;
Leggas, M ;
Sun, DX ;
Yasuda, K ;
Reid, G ;
Zelcer, N ;
Adachi, M ;
Strom, S ;
Evans, RM ;
Moore, DD ;
Borst, P ;
Schuetz, JD .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (21) :22250-22257
[4]   Endogenous antioxidant defence system in rat liver following mercury chloride oral intoxication [J].
Bando, I ;
Reus, MIS ;
Andrés, D ;
Cascales, M .
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2005, 19 (03) :154-161
[5]   Heme oxygenase-1: Redox regulation and role in the hepatic response to oxidative stress [J].
Bauer, M ;
Bauer, I .
ANTIOXIDANTS & REDOX SIGNALING, 2002, 4 (05) :749-758
[6]   Autoprotection in acetaminophen intoxication in rats: The role of liver regeneration [J].
Dalhoff, K ;
Laursen, H ;
Bangert, K ;
Poulsen, HE ;
Anderson, ME ;
Grunnet, N ;
Tygstrup, N .
PHARMACOLOGY & TOXICOLOGY, 2001, 88 (03) :135-141
[7]   Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants [J].
Dinkova-Kostova, AT ;
Holtzclaw, WD ;
Cole, RN ;
Itoh, K ;
Wakabayashi, N ;
Katoh, Y ;
Yamamoto, M ;
Talalay, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (18) :11908-11913
[8]   Challenges and limitations of gene expression profiling in mechanistic and predictive toxicology [J].
Fielden, MR ;
Zacharewski, TR .
TOXICOLOGICAL SCIENCES, 2001, 60 (01) :6-10
[9]   Autoprotection against acetaminophen toxicity in cultured rat hepatocytes: The effect of pretreatment and growth factors [J].
Grunnet, N ;
Tygstrup, N ;
Dich, J .
PHARMACOLOGY & TOXICOLOGY, 2003, 93 (03) :135-141
[10]   Advances in toxicogenomics [J].
Hayes, KR ;
Bradfield, RA .
CHEMICAL RESEARCH IN TOXICOLOGY, 2005, 18 (03) :403-414