Binary and ternary chromium(III) complexes with cellular reductants and DNA components isolated from redox type systems. Part 2. Chromium(VI)-glutathione-adenine (adenosine, ATP)

被引:6
作者
Adach, A
Cieslak-Golonka, M
机构
[1] Jan Kochanowski Univ Humanities & Sci, Inst Chem, PL-25020 Kielce, Poland
[2] Wroclaw Univ Technol, Inst Inorgan Chem & Met Rare Elements, PL-50370 Wroclaw, Poland
关键词
D O I
10.1023/B:TMCH.0000020373.42790.76
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The reduction of CrO3 with an excess of glutathione and its interaction with DNA fragments (adenine, adenosine) and the ATP nucleotide was studied by analysis of the isolated solid products. The precipitates were characterised by elemental analyses, FAB-mass spectral data, spectroscopic methods (u.v.-vis., i.r., f.i.r.) and magnetic measurements. The Cr-III complexes obtained from ternary systems appeared to be [Cr-III-glutathione] and [Cr-III-glutathione-adenine (adenosine, ATP)] species. The structure of the complexes has been proposed assuming hydrogen bonding between the Cr-III GSH complex and the DNA fragment.
引用
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页码:301 / 307
页数:7
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