The prebiotic lactosucrose modulates gut metabolites and microbiota in intestinal inflammatory rats

被引：18
作者：
Zhou, Xiaoli [1 ,2 ]
Ruan, Zheng [1 ]
Huang, Xiaoliu [1 ]
Zhou, Yan [1 ]
Liu, Shiqiang [1 ]
Yin, Yulong [3 ]
机构：
[1] Nanchang Univ, Coll Life Sci & Food Engn, State Key Lab Food Sci & Technol, Nanchang 330047, Peoples R China
[2] Guiyang Univ, Coll Food & Pharm Engn, Guiyang 550005, Peoples R China
[3] Chinese Acad Sci, Inst Subtrop Agr, Hunan Prov Engn Res Ctr Hlth Livestock, Key Lab Agroecol Proc Subtrop Reg, Changsha 410125, Hunan, Peoples R China
来源：
FOOD SCIENCE AND BIOTECHNOLOGY | 2014年 / 23卷 / 01期
基金：
中国博士后科学基金; 中国国家自然科学基金;
关键词：
lactosucrose; microflora; prebiotic; inflammation; CHAIN FATTY-ACIDS; BOWEL-DISEASE; IN-VITRO; BACTERIA; COLITIS; BIFIDOBACTERIA; FERMENTATION; MICROFLORA; BUTYRATE; MICE;
D O I：
10.1007/s10068-014-0021-8
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
The effect of lactosucrose on the short chain fatty acid (SCFA) content, the intestinal flora, the acidity, and the amino nitrogen (NH3-N) content of the intestine in inflammatory bowel disease (IBD) rats was investigated. Dietary lactosucose supplementation increased amounts of beneficial bacteria and diminished amounts of pathogenic bacteria. Lactosucrose decreased the NH3-N content in cecal and colonic digesta, compared to inflammatory rats. Lactosucrose increased the acidity in the intestinal lumen, and the acetic acid, propionic acid, and butyric acid contents in cecal and colonic digesta, compared to inflammatory rats. The butyrate content in the lactosucrose group was higher than for the inflammatory, sulfasalazine, and normal groups. Lactosucrose promoted beneficial intestinal health and prevented intestinal inflammation.
引用
收藏
页码：157 / 163
页数：7
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