Molecular characterization of a reassortant H11N9 subtype avian influenza virus isolated from a domestic duck in Eastern China

被引：10

作者：

Wu, Haibo ^{[1
]}

Peng, Xiuming ^{[1
]}

Peng, Xiaorong ^{[1
]}

Wu, Nanping ^{[1
]}

机构：

[1] Zhejiang Univ, Sch Med, Affiliated Hosp 1, State Key Lab Diag & Treatment Infect Dis,Collabo, Hangzhou 310003, Zhejiang, Peoples R China

来源：

ARCHIVES OF VIROLOGY | 2015年 / 160卷 / 10期

关键词：

Avian influenza viruses; Subtype H11N9; Domestic ducks; Reassortment; RECEPTOR-BINDING; HUMAN INFECTIONS; POULTRY MARKET; GENE POOL; A VIRUS; HEMAGGLUTININ; TRANSMISSION; RESISTANCE; SEQUENCE; H1;

D O I：

10.1007/s00705-015-2528-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

During surveillance for avian influenza viruses (AIVs) in live-poultry markets in Eastern China in 2013, an H11N9 AIV was isolated from a domestic duck. Phylogenetic analysis showed that this strain received its genes from H11, H3, H10, and H7 AIVs of poultry in China. This strain was found to be minimally pathogenic in mice and was able to replicate in mice without prior adaptation. Considering that the reassorted H11N9 viruses were isolated from domestic ducks in this study, it is possible that these ducks play an important role in the generation of novel reassorted H11 AIVs.

引用

页码：2595 / 2601

页数：7

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