Serum Tryptase Concentrations in Beekeepers With and Without Hymenoptera Venom Allergy

被引：0
|
作者：
Carballada, F. [1 ]
Alonso, M. [2 ]
Vizcaino, L. [2 ]
Coutinho, V. [2 ]
Nunez, R. [1 ]
Vidal, C. [3 ]
Boquete, M. [1 ]
Gonzalez-Quintela, A. [2 ]
机构：
[1] Hosp Lucus Augusti, Dept Allergy, Lugo, Spain
[2] Hosp Clin Univ, Dept Med, Santiago De Compostela 15706, Spain
[3] Hosp Clin Univ, Dept Allergy, Santiago De Compostela 15706, Spain
来源：
JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY | 2013年 / 23卷 / 01期
关键词：
Tryptase; Hymenoptera; Beekeeper; Venom allergy; SYSTEMIC REACTIONS; BEE VENOM; HONEYBEE; STINGS; IMMUNOTHERAPY; MASTOCYTOSIS; REACTIVITY; SEVERITY; SAFETY; LEVEL;
D O I：
暂无
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Background: Increased tryptase concentrations are a risk marker for the severity of reactions to Hymenoptera stings or venom immunotherapy. Objective: To investigate serum tryptase concentrations in beekeepers with and without Hymenoptera venom allergy (HVA). Methods: Serum tryptase concentrations were measured in adult patients with HVA (n=91, 37 of whom were beekeepers), beekeepers without HVA (n=152), and control individuals from the general adult population (n=246). Results: Multivariate analyses revealed that serum tryptase levels were positively associated with beekeeping activities (P<.001) and HVA (P<.001). Tryptase levels were also positively associated with age (P<.001) and male sex (P=.02), and negatively associated with alcohol consumption (P=.002). Conclusions: Beekeeping and HVA are independently associated with increased concentrations of serum tryptase.
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页码：30 / 36
页数：7
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