(Z)-butylidenephthalide Restores Temozolomide Sensitivity to Temozolomide-resistant Malignant Glioma Cells by Downregulating Expression of the DNA Repair Enzyme MGMT

被引：2
|
作者：
Yen, S. Y. [1 ,2 ]
Harn, H. J. [3 ]
Lin, S. Z. [4 ]
Chen, S. R. [1 ,2 ]
Lin, P. C. [5 ]
Syu, F. J. [1 ,2 ]
Hsieh, D. K. [6 ]
Huang, M. H. [7 ]
Chiou, T. W. [1 ,2 ]
机构：
[1] Natl Dong Hwa Univ, Dept Life Sci, Hualien, Taiwan
[2] Grad Inst Biotechnol, Hualien, Taiwan
[3] China Med Univ Hosp, Dept Pathol, Taichung, Taiwan
[4] China Med Univ Hosp, Ctr Neuropsychiat, Taichung, Taiwan
[5] Gwo Xi Stem Cell Appl Technol Co Ltd, Dept Res & Dev, Hsinchu, Taiwan
[6] Chaoyang Univ Technol, Dept Appl Chem, Taichung, Taiwan
[7] Natl Chung Hsing Univ, Dept Life Sci, Taichung 40227, Taiwan
来源：
EUROPEAN JOURNAL OF CANCER | 2012年 / 48卷
关键词：
D O I：
10.1016/S0959-8049(12)71541-1
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
912
引用
收藏
页码：S220 / S221
页数：2
相关论文
共 50 条
  • [1] Inhibition of DNA Repair in Combination with Temozolomide or Dianhydrogalactiol Overcomes Temozolomide-Resistant Glioma Cells
    Ohba, Shigeo
    Yamashiro, Kei
    Hirose, Yuichi
    CANCERS, 2021, 13 (11)
  • [2] Valproic Acid Downregulates the Expression of MGMT and Sensitizes Temozolomide-Resistant Glioma Cells
    Ryu, Chung Heon
    Yoon, Wan Soo
    Park, Kwang Ywel
    Kim, Seong Muk
    Lim, Jung Yeon
    Woo, Ji Sun
    Jeong, Chang Hyun
    Hou, Yun
    Jeun, Sin-Soo
    JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, 2012,
  • [3] INHIBITION OF HOMOLOGOUS RECOMBINATION RESENSITIZES TEMOZOLOMIDE-RESISTANT GLIOMA CELLS TO TEMOZOLOMIDE
    Ohba, S.
    Hirose, Y.
    NEURO-ONCOLOGY, 2017, 19 : 63 - 64
  • [4] Hyperthermia treatment overcomes temozolomide resistance in glioma cells by downregulating MGMT expression and increasing temozolomide uptake
    Lee, Chen-Ting
    Blackley, Aaron
    Landon, Chelsea
    Spasojevic, Ivan
    Kirkpatrick, John P.
    Dewhirst, Mark W.
    CANCER RESEARCH, 2014, 74 (19)
  • [5] INHIBITION OF HOMOLOGOUS RECOMBINATION RESENSITIZES TEMOZOLOMIDE-RESISTANT GLIOMA CELLS TO TEMOZOLOMIDE
    Ohba, Shigeo
    Hirose, Yuichi
    NEURO-ONCOLOGY, 2017, 19 : 64 - 64
  • [6] Differential Characterization of Temozolomide-Resistant Human Glioma Cells
    Lai, Sheng-Wei
    Huang, Bor-Ren
    Liu, Yu-Shu
    Lin, Hsiao-Yun
    Chen, Chun-Chuan
    Tsai, Cheng-Fang
    Lu, Dah-Yuu
    Lin, Chingju
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (01)
  • [7] Inhibition of DNA repair for sensitizing resistant glioma cells to temozolomide
    Kanzawa, T
    Bedwell, J
    Kondo, Y
    Kondo, S
    Germano, IM
    JOURNAL OF NEUROSURGERY, 2003, 99 (06) : 1047 - 1052
  • [8] ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts
    Yuan, Alice L.
    Ricks, Christian B.
    Bohm, Alexandra K.
    Lun, Xueqing
    Maxwell, Lori
    Safdar, Shahana
    Bukhari, Shazreh
    Gerber, Amanda
    Sayeed, Wajid
    Bering, Elizabeth A.
    Pedersen, Haley
    Chan, Jennifer A.
    Shen, Yaoqing
    Marra, Marco
    Kaplan, David R.
    Mason, Warren
    Goodman, Lindsey D.
    Ezhilarasan, Ravesanker
    Kaufmann, Ascher B.
    Cabral, Matthew
    Robbins, Steve M.
    Senger, Donna L.
    Cahill, Daniel P.
    Sulman, Erik P.
    Cairncross, J. Gregory
    Blough, Michael D.
    PLOS ONE, 2018, 13 (08):
  • [9] TEMOZOLOMIDE-INDUCED DIFFERENTIAL EXPRESSION OF DNA REPAIR GENES IN MALIGNANT GLIOMA CELLS
    Zhu, Congju
    Teng, Siaw Wei
    Cheng, Shi Yuan
    Wong, Meng Cheong
    NEURO-ONCOLOGY, 2009, 11 (06) : 904 - 904
  • [10] PARP INHIBITORS RESTORE TEMOZOLOMIDE SENSITIVITY IN MSH6-DEFICIENT TEMOZOLOMIDE-RESISTANT GLIOMA MODELS
    Higuchi, Fumi
    Wakimoto, Hiroaki
    Cahill, Daniel
    NEURO-ONCOLOGY, 2017, 19 : 67 - 67
12345