Nanoparticles in drug delivery: Past, present and future

被引：441
作者：
Couvreur, P. [1 ,2 ]
机构：
[1] Univ Paris 11, Fac Pharm, UMR CNRS 8612, IFR ITEM 141, F-92296 Chatenay Malabry, France
[2] CNRS, F-92296 Chatenay Malabry, France
来源：
ADVANCED DRUG DELIVERY REVIEWS | 2013年 / 65卷 / 01期
关键词：
Nanoparticles; Nanospheres; Nanocapsules; Polymers; Drug loading; Intracellular delivery; Drug targeting; Nanotheragnostics; Opsonization; Biodegradability; Cancer resistance; CARRIERS; NANOCAPSULES; SYSTEM;
D O I：
10.1016/j.addr.2012.04.010
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
This opinion paper relates how nanoparticles were discovered in the seventies and how the development of biodegradable materials and nanoparticle surface functionalization has allowed new treatment strategies. The reasons why only very few nanoparticle-based medicines are on the market or in late clinical trials are discussed and some new approaches are identified. Future challenges in the nanoparticle field are also identified. (c) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：21 / 23
页数：3
相关论文
共 50 条
  • [21] Hydrogel nanoparticles and nanocomposites for nasal drug/vaccine delivery
    Salatin, Sara
    Barar, Jaleh
    Barzegar-Jalali, Mohammad
    Adibkia, Khosro
    Milani, Mitra Alami
    Jelvehgari, Mitra
    [J]. ARCHIVES OF PHARMACAL RESEARCH, 2016, 39 (09) : 1181 - 1192
  • [22] On the Importance of Polyurethane and Polyurea Nanosystems for Future Drug Delivery
    Rocas, Pau
    Cusco, Cristina
    Rocas, Josep
    Albericio, Fernando
    [J]. CURRENT DRUG DELIVERY, 2018, 15 (01) : 37 - 43
  • [23] Polymeric Nanoparticles for Drug Delivery: Recent Developments and Future Prospects
    Begines, Belen
    Ortiz, Tamara
    Perez-Aranda, Maria
    Martinez, Guillermo
    Merinero, Manuel
    Arguelles-Arias, Federico
    Alcudia, Ana
    [J]. NANOMATERIALS, 2020, 10 (07) : 1 - 41
  • [24] Post-Marketing Surveillance of Prescription Drug Safety: Past, Present, and Future
    Chen, Brian K.
    Yang, Y. Tony
    [J]. JOURNAL OF LEGAL MEDICINE, 2013, 34 (02) : 193 - 213
  • [25] Red blood cell substitutes: Past, present, and future
    Chang, TMS
    [J]. ARTIFICIAL OXYGEN CARRIER: ITS FRONT LINE, 2005, 12 : 22 - 33
  • [26] Mesoporous Silica Nanoparticles for Drug Delivery
    Manzano, Miguel
    Vallet-Regi, Maria
    [J]. ADVANCED FUNCTIONAL MATERIALS, 2020, 30 (02)
  • [27] DNA nanoparticles for ophthalmic drug delivery
    de Vries, Jan Willem
    Schnichels, Sven
    Hurst, Jose
    Strudel, Lisa
    Gruszka, Agnieszka
    Kwak, Minseok
    Bartz-Schmidt, Karl-U.
    Spitzer, Martin S.
    Herrmann, Andreas
    [J]. BIOMATERIALS, 2018, 157 : 98 - 106
  • [28] Diblock copolymer nanoparticles for drug delivery
    Kwon, GS
    [J]. CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 1998, 15 (05): : 481 - 512
  • [29] Polymeric Nanoparticles for Drug Delivery in Osteoarthritis
    Pontes, Adriano P.
    Welting, Tim J. M.
    Rip, Jaap
    Creemers, Laura B.
    [J]. PHARMACEUTICS, 2022, 14 (12)
  • [30] Bioadhesive Nanoparticles for Local Drug Delivery
    Yu, Liu
    Luo, Zewen
    Chen, Tian
    Ouyang, Yaqi
    Xiao, Lingyun
    Liang, Shu
    Peng, Zhangwen
    Liu, Yang
    Deng, Yang
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (04)
12345