Coupling Reaction of Indolepyruvic Acid by StaD and Its Product: Implications for Biosynthesis of Indolocarbazole and Violacein

被引:14
作者
Asamizu, Shumpei [2 ]
Hirano, Satoshi [1 ]
Onaka, Hiroyasu [2 ]
Koshino, Hiroyuki [3 ]
Shiro, Yoshitsugu [1 ]
Nagano, Shingo [4 ]
机构
[1] RIKEN SPring 8 Ctr, Sayo, Hyogo 6795148, Japan
[2] Toyama Prefectural Univ, Dept Biotechnol, Fac Engn, Toyama 9390398, Japan
[3] RIKEN Adv Sci Inst, Dept Biol Chem, Wako, Saitama 3510198, Japan
[4] Tottori Univ, Dept Chem & Biotechnol, Grad Sch Engn, Tottori 6808552, Japan
基金
日本学术振兴会;
关键词
biosynthesis; C-C coupling; heme proteins; indolocarbazoles; staurosporine; LECHEVALIERIA-AEROCOLONIGENES ATCC-39243; GENE-CLUSTER; CHROMOPYRROLIC ACID; HETEROLOGOUS EXPRESSION; REBECCAMYCIN; STAUROSPORINE; REBC; REARRANGEMENT; DERIVATIVES; GENERATION;
D O I
10.1002/cbic.201200535
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:2495 / 2500
页数:6
相关论文
共 27 条
  • [1] Massilia sp BS-1, a Novel Violacein-Producing Bacterium Isolated from Soil
    Agematu, Hitosi
    Suzuki, Kazuya
    Tsuya, Hiroaki
    [J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2011, 75 (10) : 2008 - 2010
  • [2] Direct formation of chromopyrrolic acid from indole-3-pyruvic acid by StaD, a novel hemoprotein in indolocarbazole biosynthesis
    Asamizu, S
    Kato, Y
    Igarashi, Y
    Furumai, T
    Onaka, H
    [J]. TETRAHEDRON LETTERS, 2006, 47 (04) : 473 - 475
  • [3] VioE, a prodeoxyviolacein synthase involved in violacein biosynthesis, is responsible for intramolecular indole rearrangement
    Asamizu, Shumpei
    Kato, Yasuo
    Igarashi, Yasuhiro
    Onaka, Hiroyasu
    [J]. TETRAHEDRON LETTERS, 2007, 48 (16) : 2923 - 2926
  • [4] Characterization and Functional Modification of StaC and RebC, Which Are Involved in the Pyrrole Oxidation of Indolocarbazole Biosynthesis
    Asamizu, Shumpei
    Shiro, Yoshitsugu
    Igarashi, Yasuhiro
    Nagano, Shingo
    Onaka, Hiroyasu
    [J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2011, 75 (11) : 2184 - 2193
  • [5] In vitro biosynthesis of violacein from L-tryptophan by the enzymes VioA-E from Chromobacterium violaceum
    Balibar, Carl J.
    Walsh, Christopher T.
    [J]. BIOCHEMISTRY, 2006, 45 (51) : 15444 - 15457
  • [6] Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA
    Brady, SF
    Chao, CJ
    Handelsman, J
    Clardy, J
    [J]. ORGANIC LETTERS, 2001, 3 (13) : 1981 - 1984
  • [7] Dunford H.B., 1999, Heme Peroxidases
  • [8] ISOLATION AND SYNTHESIS OF 3,4-BIS(INDOL-3-YL)PYRROLE-2,5-DICARBOXYLIC ACID-DERIVATIVES FROM THE SLIME-MOLD LYCOGALA-EPIDENDRUM
    FRODE, R
    HINZE, C
    JOSTEN, I
    SCHMIDT, B
    STEFFAN, B
    STEGLICH, W
    [J]. TETRAHEDRON LETTERS, 1994, 35 (11) : 1689 - 1690
  • [9] Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: Insights from the AT2433 biosynthetic locus
    Gao, Qunjie
    Zhang, Changsheng
    Blanchard, Sophie
    Thorson, Jon S.
    [J]. CHEMISTRY & BIOLOGY, 2006, 13 (07): : 733 - 743
  • [10] Violacein-Producing Collimonas sp from the Sea Surface Microlayer of Costal Waters in Trondelag, Norway
    Hakvag, Sigrid
    Fjaervik, Espen
    Klinkenberg, Geir
    Borgos, Sven Even F.
    Josefsen, Kjell D.
    Ellingsen, Trond E.
    Zotchev, Sergey B.
    [J]. MARINE DRUGS, 2009, 7 (04) : 576 - 588