Antivirals Targeting Influenza A Virus

被引:89
作者
Das, Kalyan [1 ]
机构
[1] Rutgers State Univ, Ctr Adv Biotechnol & Med, Dept Chem & Chem Biol, Piscataway, NJ 08854 USA
关键词
M2 PROTON CHANNELS; STRUCTURAL BASIS; RNA-POLYMERASE; ACTIVE-SITE; IN-VITRO; NEURAMINIDASE INHIBITORS; CRYSTAL-STRUCTURE; CAP-BINDING; ION-CHANNEL; AMINO-ACID;
D O I
10.1021/jm300455c
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
[No abstract available]
引用
收藏
页码:6263 / 6277
页数:15
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共 152 条
  • [1] Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus
    Acharya, Rudresh
    Carnevale, Vincenzo
    Fiorin, Giacomo
    Levine, Benjamin G.
    Polishchuk, Alexei L.
    Balannik, Victoria
    Samish, Ilan
    Lamb, Robert A.
    Pinto, Lawrence H.
    DeGrado, William F.
    Klein, Michael L.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (34) : 15075 - 15080
  • [2] Remarkable loop flexibility in avian influenza N1 and its implications for antiviral drug design
    Amaro, Rommie E.
    Minh, David D. L.
    Cheng, Lily S.
    Lindstrom, William M., Jr.
    Olson, Arthur J.
    Lin, Jung-Hsin
    Li, Wilfred W.
    McCammon, J. Andrew
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (25) : 7764 - +
  • [3] Mechanism of 150-cavity formation in influenza neuraminidase
    Amaro, Rommie E.
    Swift, Robert V.
    Votapka, Lane
    Li, Wilfred W.
    Walker, Ross C.
    Bush, Robin M.
    [J]. NATURE COMMUNICATIONS, 2011, 2
  • [4] 3D structure of the influenza virus polymerase complex:: Localization of subunit domains
    Area, E
    Martín-Benito, J
    Gastaminza, P
    Torreira, E
    Valpuesta, JM
    Carrascosa, JL
    Ortín, J
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (01) : 308 - 313
  • [5] Functional Studies and Modeling of Pore-Lining Residue Mutants of the Influenza A Virus M2 Ion Channel
    Balannik, Victoria
    Carnevale, Vincenzo
    Fiorin, Giacomo
    Levine, Benjamin G.
    Lamb, Robert A.
    Klein, Michael L.
    DeGrado, William F.
    Pinto, Lawrence H.
    [J]. BIOCHEMISTRY, 2010, 49 (04) : 696 - 708
  • [6] Anti-influenza virus activity of peramivir in mice with single intramuscular injection
    Bantia, S
    Arnold, CS
    Parker, CD
    Upshaw, R
    Chand, P
    [J]. ANTIVIRAL RESEARCH, 2006, 69 (01) : 39 - 45
  • [7] Epidemiological, antigenic and genetic characteristics of seasonal influenza A(H1N1), A(H3N2) and B influenza viruses: Basis for the WHO recommendation on the composition of influenza vaccines for use in the 2009-2010 Northern Hemisphere season
    Barr, Ian G.
    McCauley, John
    Cox, Nancy
    Daniels, Rod
    Engelhardt, Othmar G.
    Fukuda, Keiji
    Grohmann, Gary
    Hay, Alan
    Kelso, Anne
    Klimov, Alexander
    Odagiri, Takato
    Smith, Derek
    Russell, Colin
    Tashiro, Masato
    Webby, Richard
    Wood, John
    Ye, Zhiping
    Zhang, Wenqing
    [J]. VACCINE, 2010, 28 (05) : 1156 - 1167
  • [8] Identification of Influenza Endonuclease Inhibitors Using a Novel Fluorescence Polarization Assay
    Baughman, Brandi M.
    Slavish, P. Jake
    DuBois, Rebecca M.
    Boyd, Vincent A.
    White, Stephen W.
    Webb, Thomas R.
    [J]. ACS CHEMICAL BIOLOGY, 2012, 7 (03) : 526 - 534
  • [9] STRUCTURAL BASIS FOR THE 3'-5' EXONUCLEASE ACTIVITY OF ESCHERICHIA-COLI DNA-POLYMERASE-I - A 2 METAL-ION MECHANISM
    BEESE, LS
    STEITZ, TA
    [J]. EMBO JOURNAL, 1991, 10 (01) : 25 - 33
  • [10] The Emergency Use Authorization of Peramivir for Treatment of 2009 H1N1 Influenza
    Birnkrant, Debra
    Cox, Edward
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (23) : 2204 - 2207