Clinical value of 2-deoxy-[18F]fluoro-D-glucose positron emission tomography in patients with cervical spondylotic myelopathy

被引:7
作者
Eicker, Sven O. [1 ,5 ]
Langen, Karl-Josef [2 ]
Galldiks, Norbert [2 ,3 ]
Stoffels, Gabriele [2 ]
Herdmann, Joerg [4 ]
Steiger, Hans-Jakob [1 ]
Floeth, Frank W. [1 ,4 ]
机构
[1] Univ Dusseldorf, Dept Neurosurg, D-40225 Dusseldorf, Germany
[2] Res Ctr Julich, Inst Neurosci & Med, Dusseldorf, Germany
[3] Univ Cologne, Dept Neurol, Dusseldorf, Germany
[4] St Vinzenz Hosp, Dept Spine & Pain, Dusseldorf, Germany
[5] Univ Hamburg Eppendorf, Dept Neurosurg, D-20246 Hamburg, Germany
关键词
degenerative cervical spinal stenosis; glucose hypermetabolism; prognosis; decompressive surgery; PET; SPINAL-CORD COMPRESSION; SIGNAL INTENSITY; F-18-FDG UPTAKE; LUNG-CANCER; FDG; RESOLUTION; INFLAMMATION; METASTASES; PATTERN; LESIONS;
D O I
10.3171/2013.3.FOCUS1379
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cervical spondylotic myelopathy (CSM) is one of the most common spinal cord disorders in the elderly. It is usually diagnosed by MRI, but in a significant number of patients the clinical course of CSM does not correlate with the extent of the spinal cord compression. Recent studies have suggested that a distinct metabolic pattern of the cervical cord, as assessed by PET with 2-deoxy-[F-18] fluoro-D-glucose (F-18-FDG) may predict a patient's clinical outcome after decompressive surgery for cervical spine stenosis. The authors provide an overview of the recent literature regarding the value of PET with F-18-FDG of the cervical cord in patients with CSM, paying attention to prognostic aspects and the potential role of inflammatory processes in the acute phase of the disease.
引用
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页数:7
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