Is antenatal vitamin K prophylaxis needed for pregnant women taking anticonvulsants?

被引：30

作者：

Choulika, S ^{[1
]}

Grabowski, E ^{[1
]}

Holmes, LB ^{[1
]}

机构：

[1] MassGen Hosp Children, Genet & Teratol Unit, Boston, MA USA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2004年 / 190卷 / 04期

关键词：

anticonvulsant drugs; pregnancy; vitamin K;

D O I：

10.1016/j.ajog.2004.01.041

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The objective of this cohort study of a consecutive sample of infants exposed during pregnancy to anticonvulsant drugs was to determine if the mother received late pregnancy prophylaxis with vitamin K, and if any infants had signs of hemorrhagic disease. The medical records of 204 neonates exposed to anticonvulsant drugs in utero and 77 unexposed control neonates were retrospectively reviewed. No hemorrhagic disease was observed, and the incidence of bleeding tendencies was not higher in infants exposed to these drugs compared with control infants, despite no prenatal vitamin K supplementation in all but I epileptic woman. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：882 / 883

页数：2