Doxycycline Induced Pancreatitis: An Uncommon Complication of a Common Drug

被引:5
作者
Reiche, William [1 ]
Abodunrin, Faith [1 ]
Destache, Chris [2 ]
Rangray, Rajani [3 ]
Velagapudi, Manasa [4 ]
机构
[1] CHI Hlth Creighton Univ, Dept Med, Med Ctr, Omaha, NE 68124 USA
[2] Creighton Univ, Dept Pharm Practice, Sch Pharm & Hlth Profess, Omaha, NE 68178 USA
[3] CHI Creighton Univ, Div Gastroenterol & Hepatol, Med Ctr, Omaha, NE 68124 USA
[4] CHI Creighton Univ, Div Infect Dis, Med Ctr, Omaha, NE 68124 USA
关键词
doxycycline; DIAP; drug induced acute pancreatitis; DIP; adverse drug reaction;
D O I
10.3390/pharmacy10060144
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
We describe the risk factors for the development, timing, and severity of doxycycline induced acute pancreatitis (DIAP) in two case reports and a review of prior published cases, to better understand DIAP. Clinicians must maintain a high level of suspicion for DIAP in patients presenting with acute pancreatitis, while on doxycycline therapy. The latency and severity of DIAP are variable, making diagnosis challenging. Treatment includes bowel rest, hydration, and discontinuation of doxycycline.
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页数:7
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