Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)

被引:90
作者
Al-Ayadhi, Laila Y. [1 ]
Elamin, Nadra Elyass [2 ]
机构
[1] King Saud Univ, Dept Physiol, Fac Med, Riyadh 11461, Saudi Arabia
[2] King Saud Univ, Fac Med, Autism Res & Treatment Ctr, Shaik Al Amodi Autism Res Chair, Riyadh 11461, Saudi Arabia
关键词
OXIDATIVE STRESS; ENERGY-METABOLISM; GLYCEMIC CONTROL; CHILDREN; ENZYMES; MYELOPEROXIDASE; DROMEDARIUS; GLUTATHIONE; BIOMARKER; INSULIN;
D O I
10.1155/2013/602834
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Extensive studies have demonstrated that oxidative stress plays a vital role in the pathology of several neurological diseases, including autism spectrum disorder (ASD); those studies proposed that GSH and antioxidant enzymes have a pathophysiological role in autism. Furthermore, camel milk has emerged to have potential therapeutic effects in autism. The aim of the current study was to evaluate the effect of camel milk consumption on oxidative stress biomarkers in autistic children, by measuring the plasma levels of glutathione, superoxide dismutase, and myeloperoxidase before and 2 weeks after camel milk consumption, using the ELISA technique. All measured parameters exhibited significant increase after camel milk consumption (P < 0.5). These findings suggest that camel milk could play an important role in decreasing oxidative stress by alteration of antioxidant enzymes and nonenzymatic antioxidant molecules levels, as well as the improvement of autistic behaviour as demonstrated by the improved Childhood Autism Rating Scale (CARS).
引用
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页数:8
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