Chiral separation of ibuprofen and terbutaline by nonaqueous capillary electrophoresis with conductance detection

被引：0
作者：
Deng, GH
Wei, SL
Mo, JY
机构：
[1] Guangxi Univ Nationalities, Dept Chem, Nanning, Peoples R China
[2] Zhongshan Univ, Dept Chem, Guangzhou 510275, Peoples R China
来源：
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES | 2002年 / 18卷 / 01期
关键词：
nonaqueous medium; capillary electrophoresis with conductance detection; sulfonyl beta-CD; resolution; N; N-Dimethylformamide;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In the nonaqueous N, N-dimethylformamide medium, the chiral drugs ibuprofen and terbutaline were successfully separated with sulfonyl-beta-cyclodextrin (s-beta-CD) as the chiral selector by capillary electrophoresis with conductance detection. The comparison of the effects of three CDS(beta-CD, diethylic-beta-CD, sulfonyl-beta-CD) on the chiral separation was made and the resolution mechanism was proposed.
引用
收藏
页码：16 / 19
页数：4
相关论文
共 50 条
[21]   Enantiomeric separation of five acidic drugs via capillary electrophoresis using streptomycin as chiral selector [J].
Zhang, Xuejiao ;
Qi, Shuhua ;
Liu, Chunye ;
Zhao, Xiaoli .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2017, 1063 :31-35
[22]   Chiral Separation of Oxazolidinone Analogs by Capillary Electrophoresis Using Anionic Cyclodextrins as Chiral Selectors: Emphasis on Enantiomer Migration Order [J].
Szabo, Zoltan-Istvan ;
Boda, Francisc ;
Fiser, Bela ;
Dobo, Mate ;
Szocs, Levente ;
Toth, Gergo .
MOLECULES, 2023, 28 (11)
[23]   Simultaneous chiral separation of tramadol and methadone in tablets, human urine, and plasma by capillary electrophoresis using maltodextrin as the chiral selector [J].
Naghdi, Elahe ;
Fakhari, Ali Reza .
CHIRALITY, 2018, 30 (10) :1161-1168
[24]   Doxycycline as a new chiral selector in capillary electrophoresis [J].
Jang, Min Gyeong ;
Jang, Myung Duk ;
Park, Jung Hag .
JOURNAL OF CHROMATOGRAPHY A, 2017, 1508 :176-181
[25]   Analysis of zinc dialkyl dithiophosphates by nonaqueous capillary electrophoresis and application to lubricants [J].
Thibon, VRA ;
Bartle, KD ;
Abbot, DJ ;
McCormack, KA .
JOURNAL OF MICROCOLUMN SEPARATIONS, 1999, 11 (01) :71-80
[26]   Chiral Separation of Catechin by Capillary Electrophoresis Using Mono-, Di-, Tri-succinyl-β-cyclodextrin as Chiral Selectors [J].
Kim, Hyunmyung ;
Choi, Youngjin ;
Lim, Jun ;
Paik, Seung-R ;
Jung, Seunho .
CHIRALITY, 2009, 21 (10) :937-942
[27]   Use of Sulfated Cyclofructan 6 and Sulfated Cyclodextrins for the Chiral Separation of Four Basic Pharmaceuticals by Capillary Electrophoresis [J].
Zhang, Yi Jun ;
Huang, Ming Xian ;
Zhang, Yu Ping ;
Armstrong, Daniel Wayne ;
Breitbach, Zachary S. ;
Ryoo, Jae Jeong .
CHIRALITY, 2013, 25 (11) :735-742
[28]   Investigation of enantiomeric separation of basic drugs by capillary electrophoresis using clindamycin phosphate as a novel chiral selector [J].
Chen, Bin ;
Du, Yingxiang ;
Li, Ping .
ELECTROPHORESIS, 2009, 30 (15) :2747-2754
[29]   Enantiomeric separation of amphetamine and phenylephrine by capillary zone electrophoresis with hydroxypropyl-beta-cyclodextrin as chiral additive [J].
Wang, Z ;
Huang, AJ ;
Sun, YL ;
Sun, ZP .
HRC-JOURNAL OF HIGH RESOLUTION CHROMATOGRAPHY, 1997, 20 (05) :298-299
[30]   Di-n-amyl L-tartrate-boric acid complex chiral selector in situ synthesis and its application in chiral nonaqueous capillary electrophoresis [J].
Wang, Li-Juan ;
Hu, Shao-Qiang ;
Guo, Qiao-Ling ;
Yang, Geng-Liang ;
Chen, Xing-Guo .
JOURNAL OF CHROMATOGRAPHY A, 2011, 1218 (09) :1300-1309
12345