Chiral separation of ibuprofen and terbutaline by nonaqueous capillary electrophoresis with conductance detection

被引:0
|
作者
Deng, GH
Wei, SL
Mo, JY
机构
[1] Guangxi Univ Nationalities, Dept Chem, Nanning, Peoples R China
[2] Zhongshan Univ, Dept Chem, Guangzhou 510275, Peoples R China
关键词
nonaqueous medium; capillary electrophoresis with conductance detection; sulfonyl beta-CD; resolution; N; N-Dimethylformamide;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In the nonaqueous N, N-dimethylformamide medium, the chiral drugs ibuprofen and terbutaline were successfully separated with sulfonyl-beta-cyclodextrin (s-beta-CD) as the chiral selector by capillary electrophoresis with conductance detection. The comparison of the effects of three CDS(beta-CD, diethylic-beta-CD, sulfonyl-beta-CD) on the chiral separation was made and the resolution mechanism was proposed.
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页码:16 / 19
页数:4
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