The role of central reading centers - current practices and future directions

被引：4

作者：

Tan, Colin S. ^{[1
,2
]}

Sadda, Srinivas R. ^{[3
]}

机构：

[1] Tan Tock Seng Hosp, Natl Healthcare Grp Eye Inst, Singapore 308433, Singapore

[2] Natl Healthcare Grp Eye Inst, Fundus Image Reading Ctr, Singapore, Singapore

[3] Univ Calif Los Angeles, Doheny Eye Inst, Los Angeles, CA USA

来源：

INDIAN JOURNAL OF OPHTHALMOLOGY | 2015年 / 63卷 / 05期

关键词：

Central reading center; randomized controlled trial; standard operating procedure; OPTICAL COHERENCE TOMOGRAPHY; POLYPOIDAL CHOROIDAL VASCULOPATHY; SPECTRAL-DOMAIN; RETINAL THICKNESS; AUTOFLUORESCENCE;

D O I：

10.4103/0301-4738.159866

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Central reading centers (CRCs) have several crucial roles in the conduct of clinical trials, providing key input during the study design, preparation of the operations manual, as well as site and photographer certification. They provide objective, standardized grading of images from study subjects, which determines study eligibility, and also evaluate lesion features at subsequent study visits. CRCs need to adhere strictly to Good Clinical Practice (GCP) guidelines, as well as the established standard operating procedures in order to ensure that images are graded properly. The role of CRCs will continue to evolve, and include the use of web-based image transmission and grading platforms.

引用

页码：404 / 405

页数：2

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