Diagnostic potential for miRNAs as biomarkers for pregnancy-specific diseases

被引：92

作者：

Zhao, Zhen ^{[1
]}

Moley, Kelle H. ^{[2
]}

Gronowski, Ann M. ^{[2
,3
]}

机构：

[1] NIH, Ctr Clin, Bethesda, MD 20892 USA

[2] Washington Univ, Sch Med, Dept Obstet & Gynecol, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA

来源：

CLINICAL BIOCHEMISTRY | 2013年 / 46卷 / 10-11期

关键词：

miRNA; Pregnancy; Biomarker; CIRCULATING MICRORNAS; MATERNAL CIRCULATION; HUMAN PLACENTAS; UNITED-STATES; EXPRESSION; PREECLAMPSIA; SERUM; IDENTIFICATION; PREDICTION; PROFILE;

D O I：

10.1016/j.clinbiochem.2013.01.026

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Discovery of circulating miRNAs in maternal blood has not only facilitated the understanding of their role in normal pregnancy, but also paved new avenues for biomarker discovery to detect pregnancy-associated complications, such as preeclampsia, ectopic pregnancy, gestational diabetes mellitus, fetal growth restriction, recurrent pregnancy loss, and preterm delivery. In this review, we summarize the studies to date of miRNAs in maternal circulation and placental tissue in human. This brief review does not cover all aspects of this intriguing field but focuses on some new and interesting findings of diagnostic potential for miRNAs as biomarkers for pregnancy-specific diseases. (C) 2013 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

引用

页码：953 / 960

页数：8

共 46 条

[1] A United States national reference for fetal growth
Alexander, GR
Himes, JH
Kaufman, RB
Mor, J
Kogan, M
[J]. OBSTETRICS AND GYNECOLOGY, 1996, 87 (02) : 163 - 168
[2] microRNA-155 regulates angiotensin II type 1 receptor expression in umbilical vein endothelial cells from severely pre-eclamptic pregnant women
Cheng, Weiwei
Liu, Te
Jiang, Feizhou
Liu, Chunmin
Zhao, Xinrong
Gao, Yongtao
Wang, Hui
Liu, Zhixue
[J]. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2011, 27 (03) : 393 - 399
[3] Detection and characterization of placental MicroRNAs in maternal plasma
Chim, Stephen S. C.
Shing, Tristan K. F.
Hung, Emily C. W.
Leung, Tak-yeung
Lau, Tze-kin
Chiu, Rossa W. K.
Lo, Y. M. Dennis
[J]. CLINICAL CHEMISTRY, 2008, 54 (03) : 482 - 490
[4] Cunningham F.G., 2001, WILLIAMS OBSTET, V21
[5] A comparison of fetal organ measurements by echo-planar magnetic resonance imaging and ultrasound
Duncan, KR
Issa, B
Moore, R
Baker, PN
Johnson, IR
Gowland, PA
[J]. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2005, 112 (01) : 43 - 49
[6] Placental microRNA expression in pregnancies complicated by preeclampsia
Enquobahrie, Daniel A.
Abetew, Dejene F.
Sorensen, Tanya K.
Willoughby, David
Chidambaram, Kumaravel
Williams, Michelle A.
[J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2011, 204 (02) : 178.e12 - 178.e21
[7] Serum MicroRNAs Are Promising Novel Biomarkers
Gilad, Shlomit
Meiri, Eti
Yogev, Yariv
Benjamin, Sima
Lebanony, Danit
Yerushalmi, Noga
Benjamin, Hila
Kushnir, Michal
Cholakh, Hila
Melamed, Nir
Bentwich, Zvi
Hod, Moshe
Goren, Yaron
Chajut, Ayelet
[J]. PLOS ONE, 2008, 3 (09):
[8] Serum microRNA expression in pregnancies with preeclampsia
Gunel, T.
Zeybek, Y. G.
Akcakaya, P.
Kalelioglu, I.
Benian, A.
Ermis, H.
Aydinli, K.
[J]. GENETICS AND MOLECULAR RESEARCH, 2011, 10 (04) : 4034 - 4040
[9] SCREENING FOR THE SMALL FETUS - A STUDY OF THE RELATIVE EFFICACIES OF ULTRASOUND BIOMETRY AND SYMPHYSIOFUNDAL HEIGHT
HARDING, K
EVANS, S
NEWNHAM, J
[J]. AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, 1995, 35 (02) : 160 - 164
[10] Absolute and Relative Quantification of Placenta-Specific MicroRNAs in Maternal Circulation with Placental Insufficiency-Related Complications
Hromadnikova, Ilona
Kotlabova, Katerina
Doucha, Jindrich
Dlouha, Klara
Krotta, Ladislav
[J]. JOURNAL OF MOLECULAR DIAGNOSTICS, 2012, 14 (02) : 160 - 167

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