Rate of switch from depression into mania after therapeutic sleep deprivation in bipolar depression

被引：197

作者：

Colombo, C ^{[1
]}

Benedetti, F ^{[1
]}

Barbini, B ^{[1
]}

Campori, E ^{[1
]}

Smeraldi, E ^{[1
]}

机构：

[1] Univ Milan, Sch Med, IRCCS, Ist Sci Osped San Raffaele,Dept Neuropsychiat Sci, I-20127 Milan, Italy

来源：

PSYCHIATRY RESEARCH | 1999年 / 86卷 / 03期

关键词：

affective disorder; sleep; hypomania;

D O I：

10.1016/S0165-1781(99)00036-0

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Sleep deprivation is a potentially useful non-pharmacological treatment for depression. A relationship between sleep loss and the onset of mania has been reported, so it is possible that a switch from depression into mania after sleep deprivation might be expected in bipolar depressed patients who are treated with sleep deprivation. In a sample of 206 bipolar depressed treated with three cycles of sleep deprivation, alone or in combination with heterogeneous medications, we observed a 4.85% switch rate into mania and a 5.83% switch rate into hypomania. These percentages are comparable to those observed with antidepressant drug treatments. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：267 / 270

页数：4

共 22 条

[1] SWITCH FROM DEPRESSION TO MANIA - A RECORD STUDY OVER DECADES BETWEEN 1920 AND 1982 [J].