Bacterial sRNAs: Regulation in stress

被引:104
作者
Hoe, Chee-Hock [1 ]
Raabe, Carsten A. [2 ]
Rozhdestvensky, Timofey S. [2 ]
Tang, Thean-Hock [1 ]
机构
[1] Univ Sains Malaysia, Adv Med & Dent Inst, Kepala Batas 13200, Penang, Malaysia
[2] Univ Munster, Inst Expt Pathol ZMBE, D-48149 Munster, Germany
关键词
sRNA; Stress; RNA thermometer; Riboswitch; cis-Encoded; trans-Encoded; CRISPR; FERRIC UPTAKE REGULATOR; SMALL NONCODING RNAS; THERMOSENSOR CONTROLS EXPRESSION; STAPHYLOCOCCUS-AUREUS REVEALS; HFQ-DEPENDENT REGULATION; OUTER-MEMBRANE PROTEINS; COLD-SHOCK PROTEIN; SM-LIKE PROTEIN; ESCHERICHIA-COLI; MESSENGER-RNA;
D O I
10.1016/j.ijmm.2013.04.002
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Bacteria are often exposed to a hostile environment and have developed a plethora of cellular processes in order to survive. A burgeoning list of small non-coding RNAs (sRNAs) has been identified and reported to orchestrate crucial stress responses in bacteria. Among them, cis-encoded sRNA, trans-encoded sRNA, and 5'-untranslated regions (UTRs) of the protein coding sequence are influential in the bacterial response to environmental cues, such as fluctuation of temperature and pH as well as other stress conditions. This review summarizes the role of bacterial sRNAs in modulating selected stress conditions and highlights the alliance between stress response and clustered regularly interspaced short palindromic repeats (CRISPR) in bacterial defense. (C) 2013 Elsevier GmbH. All rights reserved.
引用
收藏
页码:217 / 229
页数:13
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