A new ent-kaurane diterpenoid from Isodon nervosus

被引：4
|
作者：
Yana, FuLin [1 ]
Wang, ChunMing [2 ]
Gua, LanQing [1 ]
Zhang, JiXia [1 ]
Bai, SuPing [1 ]
机构：
[1] Xinxiang Med Univ, Coll Pharm, Xinxiang 453003, Peoples R China
[2] Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Peoples R China
来源：
JOURNAL OF CHEMICAL RESEARCH-S | 2008年 / 09期
关键词：
labiatae; Isodon nervosus; ent-kaurane; diterpenoid; cytotoxicity;
D O I：
10.3184/030823408X349934
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new ent-kaurane diterpenoid, 6 beta,7 beta,13 alpha-trihydroxy-1 alpha-acetoxy-7 alpha,20-epoxy-ent-kaur-16-en-15-one (1) and five known compounds, epinodosinol (2), isodocarpin (3), nodosin (4), enmedol (5), nervosanin B (6), were isolated from the aerial part of Isodon nervosus. The structure of the new compound was determined by spectral methods (1D-,2D-NMR and MS). Four of the compounds were tested for their cytotoxicity towards HL60, SMMC-7721 and Hela cells.
引用
收藏
页码：522 / 524
页数：3
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