Asymmetric β-Boration of α,β-Unsaturated Esters with Chiral (NHC)Cu Catalysts

被引：176

作者：

Lillo, Vanesa ^{[3
]}

Prieto, Auxiliadora ^{[2
]}

Bonet, Amadeu ^{[3
]}

Mar Diaz-Requejo, M. ^{[1
]}

Ramirez, Jesus ^{[3
]}

Perez, Pedro J. ^{[1
]}

Fernandez, Elena ^{[3
]}

机构：

[1] Univ Huelva, CSIC, Unidad Asociada, Dept Quim & Ciencia Mat,Lab Catalisis Homogenea, Huelva 21007, Spain

[2] Univ Huelva, Dept Ingn Quim Quim Fis & Quim Organ, Huelva 21007, Spain

[3] Univ Rovira & Virgili, Dpt Quim Fis & Inorgan, Tarragona 43005, Spain

来源：

ORGANOMETALLICS | 2009年 / 28卷 / 02期

关键词：

N-HETEROCYCLIC CARBENES; CARBONYL-COMPOUNDS; RATE ACCELERATION; DIBORON REAGENTS; CU; BORYLCOPPER; DIBORATION; ADDITIONS;

D O I：

10.1021/om800946k

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Copper complexes containing chiral N-heterocyclic carbene ligands catalyze the regioselective nucleophilic boryl attack at the beta-carbon of alpha,beta-unsaturated esters with enantioselectivities up to 74% ee, depending on the nature of the ester group.

引用

页码：659 / 662

页数：4

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