Single-sided device for magnetic particle imaging

被引:73
作者
Sattel, Timo F. [1 ]
Knopp, Tobias [1 ]
Biederer, Sven [1 ]
Gleich, Bernhard [2 ]
Weizenecker, Juergen [2 ]
Borgert, Joern [2 ]
Buzug, Thorsten M. [1 ]
机构
[1] Med Univ Lubeck, Inst Med Engn, D-23538 Lubeck, Germany
[2] Philips Technol GmbH Forschungslab, D-22335 Hamburg, Germany
关键词
D O I
10.1088/0022-3727/42/2/022001
中图分类号
O59 [应用物理学];
学科分类号
摘要
Recently, a new imaging modality called magnetic particle imaging (MPI) was introduced. The method is capable of imaging the distribution of superparamagnetic nanoparticles at high sensitivity, high resolution and high imaging speed by exploiting their non-linear magnetization curve. Up to now, all published simulation as well as experimental work uses a scanner setup, where the field of view (FOV) lies in between a symmetric coil configuration. This, however, poses a size limitation for the specimens. In this paper, we present a feasibility study of a new, so-called single-sided scanner, which is applied to the object of interest merely from one side. Thus, the problem of the specimen fitting into the scanner no longer exists, which denotes a major step for MPI. To date, the FOV of the single-sided device is limited to one dimension. First experimental results on imaging phantoms containing a superparamagnetic fluid show a resolution of up to 1mm and are indeed promising.
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页数:5
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