Annulative tandem reactions based on Pd0/tBu3P-catalyzed cross-coupling and C(sp3)-H bond activation

被引：119
作者：
Dong, CG
Hu, QS [1 ]
机构：
[1] CUNY Coll Staten Isl, Dept Chem, Staten Isl, NY 10314 USA
[2] CUNY, Grad Ctr, Staten Isl, NY 10314 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 14期
关键词：
C-H activation; cross-coupling; palladium phosphanes; tandem reactions;
D O I：
10.1002/anie.200504310
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) All together now: Pd0/tBu 3P-catalyzed annulative tandem reactions of 1,2-dihalobenzenes were carried out with hindered Grignard reagents. This new type of tandem reaction is believed to occur through cross-coupling followed by cyclization with C(sp 3)-H bond activation as the key step and allows one-step access to potentially useful substituted fluorenes in high yield from readily available 1,2-dibromobenzenes and 1-bromo-2-iodobenzene. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
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收藏
页码：2289 / 2292
页数：4
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