IN VIVO GUIDANCE AND ASSESSMENT OF LIVER RADIO-FREQUENCY ABLATION WITH ACOUSTIC RADIATION FORCE ELASTOGRAPHY

被引:81
作者
Fahey, Brian J. [1 ]
Nelson, Rendon C. [1 ,2 ]
Hsu, Stephen J. [1 ]
Bradway, David P. [1 ]
Dumont, Douglas M. [2 ]
Trahey, Gregg E. [1 ,2 ]
机构
[1] Duke Univ, Dept Biomed Engn, Med Ctr, Durham, NC 27708 USA
[2] Duke Univ, Dept Radiol, Med Ctr, Durham, NC 27708 USA
关键词
Ultrasound; Ultrasonic imaging; Acoustic radiation force; Abdominal imaging; Elastography; Radiofrequency Ablation; Clinical trial;
D O I
10.1016/j.ultrasmedbio.2008.03.006
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The initial results from clinical trials investigating the utility of acoustic radiation force impulse (ARFI) imaging for use with radio-frequency ablation (RFA) procedures in the liver are presented. To date, data have been collected from 6 RFA procedures in 5 unique patients. Large displacement contrast was observed in ARFI images of both pre-ablation malignancies (mean 7.5 dB, range 5.7-11.9 dB) and post-ablation thermal lesions (mean 6.2 dB, range 5.1-7.5 dB). In general, ARFI images provided superior boundary definition of structures relative to the use of conventional sonography alone. Although further investigations are required, initial results are encouraging and demonstrate the clinical promise of the ARFI method for use in many stages of RFA procedures. (E-mail: bfahey04@gmail.com) (C) 2008 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码:1590 / 1603
页数:14
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