Chitosan scaffolds, films and microgranules for medical application - preparation and drug release studies

被引：4
作者：
Mucha, Maria [1 ]
Michalak, Iwona [1 ]
Balcerzak, Jacek [1 ]
Tylman, Michal [1 ]
机构：
[1] Tech Univ Lodz, Fac Proc & Environm Engn, PL-90924 Lodz, Poland
来源：
POLIMERY | 2012年 / 57卷 / 10期
关键词：
scaffolds; microgranules; kinetics of drug release; lyophilization; electrolysis;
D O I：
10.14314/polimery.2012.714
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The paper presents various structural forms of chitosan for medical applications. These are films and microgranules for transdermal and oral application of active substances and porous scaffolds constituting support for the regenerating cells in bone tissue engineering. Tested porous systems were obtained by lyophilization or electrolytic method. Methods of sample preparation and the morphology analyses were presented. The influence of water on properties of transdermal systems and changes in release kinetics of active substances for microgranules and films under modification of their structures, were carried out.
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页码：714 / 721
页数：8
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