New treatment strategies for male lower urinary tract symptoms

被引：0

作者：

da Silva, L. F. Arenas ^{[1
]}

Schoenthaler, M. ^{[2
]}

Cruz, F. ^{[3
,4
,5
]}

Gratzke, C. ^{[6
]}

Zumbe, J. ^{[7
]}

Stenzl, A. ^{[1
]}

Amend, B. ^{[1
]}

Sievert, K. -D. ^{[1
]}

机构：

[1] Univ Klinikum Tubingen, Urol Klin, D-72076 Tubingen, Germany

[2] Univ Freiburg Klinikum, Urol Abt, Freiburg, Germany

[3] Hosp Sao Joao, Dept Urol, Oporto, Portugal

[4] Hosp Sao Joao, IBMC, Oporto, Portugal

[5] Univ Porto, P-4100 Oporto, Portugal

[6] LMU Munchen, Urol Klin & Poliklin, Munich, Germany

[7] Klinikum Leverkusen, Urol Klin, Leverkusen, Germany

来源：

UROLOGE | 2012年 / 51卷 / 12期

关键词：

Urinary tract; lower; Prostate syndrome; benign; Innovative therapy procedures; Injection; intraprostatic; Therapeutic procedures; minimally invasive; BENIGN PROSTATIC HYPERPLASIA; RANDOMIZED CLINICAL-TRIAL; TOXIN TYPE-A; BOTULINUM TOXIN; URETHRAL LIFT; ANTAGONIST CETRORELIX; CALCITRIOL ANALOG; INJECTION; GROWTH; MEN;

D O I：

10.1007/s00120-012-3032-1

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

For patients with lower urinary tract symptoms (LUTS), alpha 1-adrenoreceptor inhibitors and 5-alpha reductase inhibitors as well as their combination are considered the gold standard. In addition, anticholinergic agents are being introduced as monotherapy or in combination with alpha 1-adrenocepetor inhibitors for patients with predominant storage disorders. Phosphodiesterase 5 (PDE5) inhibitors are often the best option for patients with LUTS who also suffer from erectile dysfunction. Recently, novel treatment options have been presented and intraprostatic injection of various agents, such as botulinum toxin A, NX-1207 and PRX302 has shown promising initial results. In addition, innovative minimally invasive treatment options, such as UroLiftA (R) appear to be efficacious and safe in this patient cohort. Particular emphasis should be laid on patients with LUTS and concomitant sexual disorders.

引用

页码：1697 / 1702

页数：6

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