Efficient TCT-catalyzed synthesis of 1,5-benzodiazepine derivatives under mild conditions

被引：37

作者：

Kuo, Chun-Wei ^{[1
]}

Wang, Chun-Chao ^{[1
]}

Kavala, Veerababurao ^{[1
]}

Yao, Ching-Fa ^{[1
]}

机构：

[1] Natl Taiwan Normal Univ, Dept Chem, Taipei 116, Taiwan

来源：

MOLECULES | 2008年 / 13卷 / 09期

关键词：

benzodiazepines; 2,4,6-trichloro-1,3,5-triazine; enolizable ketones; o-phenylenediamines;

D O I：

10.3390/molecules13092313

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

2,4,6-Trichloro-1,3,5-triazine (TCT) efficiently catalyzed the condensation reactions between 1,2-diamines and various enolizable ketones to afford 1,5-benzodiazepines in good to excellent yields. Simple and mild reaction conditions, the use of a cheap catalyst and easy workup and isolation are notable features of this method.

引用

页码：2313 / 2325

页数：13

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