Rheumatoid arthritis-associated aortitis: a case report and literature review

被引:21
作者
Kaneko, Shunta [1 ]
Yamashita, Hiroyuki [1 ]
Sugimori, Yusuke [1 ]
Takahashi, Yuko [1 ]
Kaneko, Hiroshi [1 ]
Kano, Toshikazu [1 ]
Mimori, Akio [1 ]
机构
[1] Natl Ctr Global Hlth & Med, Div Rheumat Dis, Tokyo 1628655, Japan
关键词
Rheumatoid arthritis; Rheumatoid vasculitis; Aortitis; EXTRAARTICULAR MANIFESTATIONS; ARTERITIS; REGURGITATION; VASCULITIS;
D O I
10.1186/2193-1801-3-509
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disorder that primarily affects the synovial joints. Rheumatoid vasculitis (RV) is an extra-articular manifestation of RA, and its association with aortitis is rare and not widely recognised. Here, we report the case of a 69-year-old woman with RA-associated aortitis and review the literature on rheumatoid aortitis. The mean oral steroid dose administered to RA-associated aortitis patients was 46.3 mg/day prednisolone (PSL). In our patient, the aortitis was also thought to be due to RV because she had findings of RV, such as cutaneous ulceration and a high rheumatoid factor titre, and because a moderate PSL dose dramatically improved the clinical findings. RA-associated aortitis, if left untreated, can be fatal; therefore, early detection and treatment initiation is very important.
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页数:7
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