Plane-wave fluorescence tomography with adaptive finite elements

被引：26

作者：

Joshi, A ^{[1
]}

Bangerth, W

Hwang, K

Rasmussen, J

Sevick-Muraca, EM

机构：

[1] Baylor Coll Med, Dept Radiol, Photon Migrat Labs, Houston, TX 77030 USA

[2] Texas A&M Univ, Dept Math, College Stn, TX 77840 USA

来源：

OPTICS LETTERS | 2006年 / 31卷 / 02期

关键词：

D O I：

10.1364/OL.31.000193

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We present three-dimensional fluorescence yield tomography of a tissue phantom in a noncontact reflectance imaging setup. The method employs planar illumination with modulated light and frequency domain fluorescence measurements made on the illumination plane. An adaptive finite-element algorithm is used to handle the ill-posed and computationally demanding inverse image reconstruction problem. Tomographic images of fluorescent targets buried at 1-2 cm depths from the illumination surface demonstrate the feasibility of fluorescence tomography from reflectance tomography in clinically relevant tissue volumes. (c) 2006 Optical Society of America.

引用

页码：193 / 195

页数：3

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