Watchful Waiting after Radiochemotherapy in Rectal Cancer: When Is It Feasible?

被引：20

作者：

Gani, Cihan ^{[1
,2
]}

Kirschniak, Andreas ^{[3
]}

Zips, Daniel ^{[1
,2
]}

机构：

[1] Univ Hosp Tubingen, Dept Radiat Oncol, Hoppe Seyler Str 3, DE-72076 Tubingen, Germany

[2] German Canc Res Ctr, Heidelberg & German Consortium Translat Canc Res, Partner Site Tubingen, Tubingen, Germany

[3] Univ Hosp Tubingen, Dept Surg, Tubingen, Germany

来源：

VISCERAL MEDICINE | 2019年 / 35卷 / 02期

关键词：

Cancer; Complete response; Organ preservation; Radiotherapy; Rectal cancer; CLINICAL COMPLETE RESPONDERS; ORGAN PRESERVATION; CHEMORADIATION THERAPY; REGIONAL HYPERTHERMIA; LOCAL EXCISION; OPEN-LABEL; MULTICENTER; POLICY;

D O I：

10.1159/000499167

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A "watch and wait" strategy in rectal cancer is increasingly considered in patients who achieve an excellent response to radiotherapy. While a growing number of studies have shown the feasibility of this strategy in selected patients, the optimal therapeutic regimen to maximize response rates still needs to be established. Furthermore, accurate response prediction and the management of minor residual findings after radiotherapy remain a matter of debate. Finally, concerns regarding the long-term oncological safety of the "watch and wait" approach have been expressed. Therefore, the present review aims to address the open questions in the context of a "watch and wait" strategy and focuses on the diagnosis of a clinical complete response and the ideal management thereafter. (C) 2019 S. Karger AG, Basel

引用

页码：119 / 123

页数：5

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