CATALYST-FREE, ONE-POT, EXPEDITIOUS SYNTHESIS OF AMINOALKYLNAPHTHOLS AT ROOM TEMPERATURE

被引：24

作者：

Mukhopadhyay, Chhanda ^{[1
]}

Rana, Sunil ^{[1
]}

Butcher, Ray J. ^{[2
]}

机构：

[1] Univ Calcutta, Dept Chem, Kolkata 700009, India

[2] Howard Univ, Dept Chem, Washington, DC 20059 USA

来源：

SYNTHETIC COMMUNICATIONS | 2012年 / 42卷 / 20期

关键词：

Aminoalkylnaphthols; catalyst-free; dichloromethane; one-pot synthesis; room temperature; RICH AROMATIC-COMPOUNDS; ENANTIOSELECTIVE ADDITION; BETTI BASE; ASYMMETRIC TRANSFORMATION; STEREOSELECTIVE SYNTHESIS; ARYL ALDEHYDES; CHIRAL LIGANDS; DIETHYLZINC; AMINONAPHTHOLS; DERIVATIVES;

D O I：

10.1080/00397911.2011.575524

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aminoalkylnaphthols possess several biological and catalytic activities. A methodology has been developed for the multicomponent one-pot synthesis of aminoalkylnaphthols in dichloromethane under catalyst-free conditions at room temperature. The present approach possesses several advantages such as excellent yields, quick reaction time, mild reaction conditions, and very easy purification processes. Thirteen new compounds in addition to six known compounds have been synthesized by this methodology.

引用

页码：3077 / 3088

页数：12

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