Sinonasal Pure Yolk Sac Tumor: A Case Report and Literature Review

被引：11
作者：
Chuang, Huei Chieh [1 ]
Kang, Chung-Jan [2 ]
Lee, Li-yu [1 ]
机构：
[1] Chang Gung Mem Hosp, Dept Pathol, Kwei Shan, Taoyuan County, Taiwan
[2] Chang Gung Mem Hosp, Dept Otolaryngol, Kwei Shan, Taoyuan County, Taiwan
来源：
FETAL AND PEDIATRIC PATHOLOGY | 2014年 / 33卷 / 03期
关键词：
sinonasal yolk sac tumor; endodermal sinus tumor; extragonadal germ cell tumor; ENDODERMAL SINUS TUMOR; DIFFERENTIAL-DIAGNOSIS; MATURE TERATOMA; CARCINOMA; SALL4; HEAD; EXPRESSION; PITFALL; OVARY;
D O I：
10.3109/15513815.2013.839013
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Extragonadal pure yolk sac tumor of sinonasal origin is very rare. We report herein a case with sinonasal yolk sac tumor in a 1 year and 3 months old girl. The initial complaint was persistent nasal bleeding for about 2 months. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a lobulated soft tissue mass in paranasal sinus that extended to oral cavity, nasopharynx, and oropharynx. The histology showed typical features of yolk sac tumor and the positive immunohistochemical staining of SALL4 and alpha-fetoprotein. After tumor excision, adjuvant chemotherapy of JEB regimen was prescribed. After the follow-up for 13-months, a-fetoprotein was normal and neither tumor progression nor metastasis was found. We review the previous literature and discuss the etiology, histology, treatment, and the prognosis of the rare sinonasal yolk sac tumor.
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收藏
页码：127 / 134
页数：8
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