Equity in Health: Consideration of Race and Ethnicity in Precision Medicine

被引:16
作者
Edwards, Todd L. [1 ,2 ]
Breeyear, Joseph [1 ,2 ]
Piekos, Jacqueline A. [2 ,3 ]
Edwards, Digna R. Velez [2 ,3 ,4 ]
机构
[1] Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN USA
[2] Vanderbilt Univ, Med Ctr, Vanderbilt Genet Inst, 221 Kirkland Hall, Nashville, TN 37235 USA
[3] Vanderbilt Univ, Med Ctr, Dept Obstet & Gynecol, Div Quantitat Sci, 221 Kirkland Hall, Nashville, TN 37235 USA
[4] Vanderbilt Univ, Med Ctr, Dept Biomed Informat, 221 Kirkland Hall, Nashville, TN 37235 USA
基金
美国国家卫生研究院;
关键词
DISEASE; POPULATIONS;
D O I
10.1016/j.tig.2020.07.001
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The causes for disparities in implementation of precision medicine are complex, due in part to differences in clinical care and a lack of engagement and recruitment of under-represented populations in studies. New tools and large genetic cohorts can change these circumstances and build access to personalized medicine for disadvantaged populations.
引用
收藏
页码:807 / 809
页数:3
相关论文
共 16 条
[1]  
[Anonymous], 2015, POPULATION ESTIMATES
[2]  
Banwell Cathy, 2005, Health Care Women Int, V26, P340, DOI 10.1080/07399330590925862
[3]   Genetic testing strategies in the newborn [J].
Carroll, Jeanne ;
Wigby, Kristen ;
Murray, Sarah .
JOURNAL OF PERINATOLOGY, 2020, 40 (07) :1007-1016
[4]   Population-based genetic testing for Women's cancer prevention [J].
Evans, Olivia ;
Gaba, Faiza ;
Manchanda, Ranjit .
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY, 2020, 65 :139-153
[5]   Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019-COVID-NET, 14 States, March 1-30, 2020 [J].
Garg, Shikha ;
Kim, Lindsay ;
Whitaker, Michael ;
O'Halloran, Alissa ;
Cummings, Charisse ;
Holstein, Rachel ;
Prill, Mila ;
Chai, Shua J. ;
Kirley, Pam D. ;
Alden, Nisha B. ;
Kawasaki, Breanna ;
Yousey-Hindes, Kimberly ;
Niccolai, Linda ;
Anderson, Evan J. ;
Openo, Kyle P. ;
Weigel, Andrew ;
Monroe, Maya L. ;
Ryan, Patricia ;
Henderson, Justin ;
Kim, Sue ;
Como-Sabetti, Kathy ;
Lynfield, Ruth ;
Sosin, Daniel ;
Torres, Salina ;
Muse, Alison ;
Bennett, Nancy M. ;
Billing, Laurie ;
Sutton, Melissa ;
West, Nicole ;
Schaffner, William ;
Talbot, H. Keipp ;
Aquino, Clarissa ;
George, Andrea ;
Budd, Alicia ;
Brammer, Lynnette ;
Langley, Gayle ;
Hall, Aron J. ;
Fry, Alicia .
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2020, 69 (15) :458-464
[6]   Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans [J].
Genovese, Giulio ;
Friedman, David J. ;
Ross, Michael D. ;
Lecordier, Laurence ;
Uzureau, Pierrick ;
Freedman, Barry I. ;
Bowden, Donald W. ;
Langefeld, Carl D. ;
Oleksyk, Taras K. ;
Knob, Andrea L. Uscinski ;
Bernhardy, Andrea J. ;
Hicks, Pamela J. ;
Nelson, George W. ;
Vanhollebeke, Benoit ;
Winkler, Cheryl A. ;
Kopp, Jeffrey B. ;
Pays, Etienne ;
Pollak, Martin R. .
SCIENCE, 2010, 329 (5993) :841-845
[7]  
GUTHRIE R, 1963, PEDIATRICS, V32, P338
[8]   Insurance coverage, medical care use, and short-term health changes following an unintentional injury or the onset of a chronic condition [J].
Hadley, Jack .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 297 (10) :1073-1084
[9]   Clinical use of current polygenic risk scores may exacerbate health disparities [J].
Martin, Alicia R. ;
Kanai, Masahiro ;
Kamatani, Yoichiro ;
Okada, Yukinori ;
Neale, Benjamin M. ;
Daly, Mark J. .
NATURE GENETICS, 2019, 51 (04) :584-591
[10]  
Mautz B.S., 2019, BIORXIV, DOI [10.1101/697581, DOI 10.1101/697581]