Living Donor Intestinal Transplantation

被引:19
作者
Tzvetanov, Ivo G. [1 ]
Tulla, Kiara A. [1 ]
D'Amico, Giuseppe [1 ]
Benedetti, Enrico [1 ]
机构
[1] Univ Illinois, Dept Surg, 840 SouthWood St,Suite 402, Chicago, IL 60612 USA
关键词
Intestinal failure; Pediatric recipients; Living donor small bowel transplantation; Combined living donor intestinal/liver transplantation; SMALL-BOWEL TRANSPLANTATION; PARENTERAL-NUTRITION; 1ST REPORT; FOLLOW-UP; LIVER; EXPERIENCE; CHILDREN; FAILURE; IMPACT;
D O I
10.1016/j.gtc.2018.01.008
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Living donor intestinal transplant (LDIT) has been improved, leading to results comparable with those obtained with deceased donors. LDIT should be limited to specific indications and patient selection. The best indication is combined living donor intestinal/liver transplant in pediatric recipients with intestinal and hepatic failure; the virtual elimination of waiting time may avoid the high mortality experienced by candidates on the deceased waiting list. Potentially, LDIT could be used in highly sensitized recipients to allow the application of desensitization protocols. In the case of available identical twins or HLA-identical sibling, LDIT has a significant immunologic advantage and should be offered.
引用
收藏
页码:369 / +
页数:13
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