Bordetella pertussis in adolescents students in Mexico City

被引:11
作者
Tome Sandoval, Patricia [1 ]
Torres Arreola, Laura del Pilar [2 ]
Romero Quechol, Guillermina [3 ,4 ]
Guiscafre Gallardo, Hector [3 ,4 ]
机构
[1] Edificio Acad Nacl Med, IMSS, Ctr Med Nacl Siglo 21, Div Desarrollo Invest, Cuauhtemoc 06725, Mexico
[2] IMSS, Div Excelencia Clin, Coordinac Unidades Med Alta Especialidad, Mexico City, DF, Mexico
[3] IMSS, Unidad Invest Epidemiol, Mexico City, DF, Mexico
[4] IMSS, Serv Salud, Mexico City, DF, Mexico
来源
REVISTA DE SAUDE PUBLICA | 2008年 / 42卷 / 04期
关键词
Bordetella pertussis; adolescent; cough; epidemiology; contact tracing; Mexico;
D O I
10.1590/S0034-89102008000400014
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
OBJECTIVE: To estimate seroprevalence of Bordetella pertussis in Students and their community. METHODS: A total of 12,273 adolescent Student,; aged 12 to 15 years from 14 public high schools in Mexico City were Studied from September 2002 to March 2003. Nasopharyngeal samples were collected from those adolescents With Whooping cough for more than 14 days. Infection was confirmed using polymerase chain reaction (PCR). All Students, school staff and family exposed to PCR-confirmed cases were tested. RESULTS: Whooping cough rate was 5 to 1,000 Students. Of those students (61) who were identified with whooping cough for more than 14 days, 20 (32.8%) were positive to Bordetella pertussis. Of 152 people exposed (contacts) to these cases, 16 (10.6%) were positive and only eight (50%) had whooping Cough. One of these exposed (contacts) was the principal of a school that had more than 60% positive cases (12/20) and who was also a teacher of 10 infected Students. Of 29 family members tested, eight (27.6%) were positive and from three different families. CONCLUSIONS: The Study results show a similar rate of whooping Cough in adolescents as seen in other countries. Since persistent Cough is not always clinically seen in all infected individuals, there may be asymptomatic cases of Bordetella infection.
引用
收藏
页码:679 / 683
页数:5
相关论文
共 11 条
[1]   Morbidity of pertussis in adolescents and adults [J].
De Serres, G ;
Shadmani, R ;
Duval, B ;
Boulianne, N ;
Déry, P ;
Fradet, MD ;
Rochette, L ;
Halperin, SA .
JOURNAL OF INFECTIOUS DISEASES, 2000, 182 (01) :174-179
[2]   Pertussis outbreak in a poorly immunized community [J].
del Pozo, JS ;
Moreno, JCS ;
Sancho, MJG ;
Lledó, ER ;
de Ory Manchón, F ;
Díaz, MF .
MEDICINA CLINICA, 2002, 119 (16) :601-604
[3]   Bordetella pertussis detection by real-time PCR, immunofluorescence and culture:: prospective evaluation and molecular epidemiology [J].
Garcia-Martinez, Jesus ;
Chaves, Fernando ;
Salto, Efren ;
Otero, Joaquin R. .
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA, 2006, 24 (08) :500-504
[4]   Microbiological and serological diagnosis of pertussis [J].
Hallander, HO .
CLINICAL INFECTIOUS DISEASES, 1999, 28 :S99-S106
[5]   Whooping cough in school age children with persistent cough: prospective cohort study in primary care [J].
Harnden, Anthony ;
Grant, Cameron ;
Harrison, Timothy ;
Perera, Rafael ;
Brueggemann, Angela B. ;
Mayon-White, Richard ;
Mant, David .
BRITISH MEDICAL JOURNAL, 2006, 333 (7560) :174-177
[6]   A boarding school outbreak of pertussis in adolescents: value of laboratory diagnostic methods [J].
Horby, P ;
Macintyre, CR ;
McIntyre, PB ;
Gilbert, GL ;
Staff, M ;
Hanlon, M ;
Heron, LG ;
Cagney, M ;
Bennett, C .
EPIDEMIOLOGY AND INFECTION, 2005, 133 (02) :229-236
[7]   DURATION OF EFFECTIVENESS OF PERTUSSIS-VACCINE - EVIDENCE FROM A 10 YEAR COMMUNITY STUDY [J].
JENKINSON, D .
BRITISH MEDICAL JOURNAL, 1988, 296 (6622) :612-614
[8]   Pertussis outbreak in an elementary school with high vaccination coverage [J].
Khetsuriani, N ;
Bisgard, K ;
Prevots, DR ;
Brennan, M ;
Wharton, M ;
Pandya, S ;
Poppe, A ;
Flora, K ;
Dameron, G ;
Quinlisk, P .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2001, 20 (12) :1108-1112
[9]   Issues associated with and recommendations for using PCR to detect outbreaks of pertussis [J].
Lievano, FA ;
Reynolds, MA ;
Waring, AL ;
Ackelsberg, J ;
Bisgard, KM ;
Sanden, GN ;
Guris, D ;
Golaz, A ;
Bopp, DJ ;
Limberger, RJ ;
Smith, PF .
JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (08) :2801-2805
[10]  
Sapian-Lopez L A, 1992, Salud Publica Mex, V34, P177