Pediatric Intensive Care Treatment of Uncontrolled Status Epilepticus

被引：46
作者：
Wilkes, Ryan [1 ]
Tasker, Robert C. [1 ,2 ]
机构：
[1] Boston Childrens Hosp, Dept Anesthesia Pain & Perioperat Med, Div Crit Care, Boston, MA 02115 USA
[2] Boston Childrens Hosp, Dept Neurol, Boston, MA 02115 USA
来源：
CRITICAL CARE CLINICS | 2013年 / 29卷 / 02期
关键词：
Status epilepticus; Super-refractory; FIRES epilepsy; Anesthesia; Pediatric; REFRACTORY STATUS EPILEPTICUS; CONVULSIVE STATUS EPILEPTICUS; EPILEPSY SYNDROME FIRES; ISOFLURANE; CHILDREN; SEIZURES; MIDAZOLAM; MANAGEMENT; THERAPY; LONG;
D O I：
10.1016/j.ccc.2012.11.007
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Pediatric Intensive Care Treatment of Uncontrolled Status Epilepticus Ryan Wilkes and Robert C. Tasker The critically ill mechanically ventilated child with ongoing seizures that are refractory to any treatment presents a distinct challenge in pediatric neurocritical care. The evidence base from randomized controlled trials on which anti-epileptic drug (AED) strategy should be used is inadequate. This review of refractory and super-refractory status epilepticus summarizes recent pediatric case series regarding definitions, the second-tier AED therapies once initial anticonvulsants have failed, and the experience of high-dose midazolam, barbiturate anesthesia, and volatile anesthetics for uncontrolled status epilepticus.
引用
收藏
页码：239 / +
页数：21
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