Relapsing non-traumatic intracerebral hemorrhage: study of 28 patients

被引:0
作者
Arboix, Adria [1 ,2 ]
Massons, Joan [1 ]
Garcia-Eroles, Luis [3 ]
Comes, Emili [1 ]
Targa, Cecilia [1 ]
Oliveres, Montserrat [1 ]
机构
[1] Univ Barcelona, Unidad Enfermedades Vasc Cerebrales, Serv Neurol, Capio Hosp Univ Sagrat Cor, Barcelona 7, Spain
[2] Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Resp CB06 06, Madrid, Spain
[3] Hosp Badalona Germans Trias & Pujol, Unitat Org & Sistemes Informacio, Barcelona, Spain
来源
MEDICINA CLINICA | 2012年 / 139卷 / 12期
关键词
Intracerebral hemorrhage; Hemorrhagic stroke recurrence; Predictive factors; Multivariate analysis; PATIENTS AGED 85; STROKE; MECHANISMS; RISK;
D O I
10.1016/j.medcli.2012.05.009
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and objetive: To characterize the clinical factors and prognosis and identify determinants of hemorrhage recurrence (HCR) in patients with acute non-traumatic intracerebral hemorrhage. Patients and method: Stroke patterns were studied in 28 consecutive recurrent non-traumatic intracerebral hemorrhage patients admitted to the Department of Neurology of the Sagrat Car Hospital of Barcelona for a 19 year period. Demographic, risk factors, clinical, neuroimaging and outcome variables were analyzed and compared with patients with first-ever non-traumatic intracerebral hemorrhage (n = 380) to identify predictors of hemorrhage recurrence. Significant variables were entered into a multivariate logistic regression analysis. Results: HCR accounted for 6.8% of all patients with acute consecutive non-traumatic intracerebral hemorrhages. The HCR were mostly lobar (67.9%). Other topographies include: thalamus (10.7%), capsule-ganglionar (7.1%), intraventricular (3.6%) and multiple topographies (10.7%). Although the HCR have poor prognosis, it is not worse compared to the first-ever intracerebral hemorrhages, both at the high hospital mortality (17.9 vs. 28.2%) as the low frequency of absence of limitation at discharge (3.6 vs. 6.1%). The clinical profile significantly associated with HCR was: valvular heart disease (odds ratio [OR] 5.32; 95% confidence interval [95% CI] 1.45-19.47), lobar topography (OR 3.53,95% IC 1.53-8.13), and the presence of nausea and vomiting (OR 2.43, 95% IC 1.06-5.52). Conclusions: HCR constitute less than one tenth of non-traumatic intracerebral hemorrhages and are most commonly located in the brain lobes. Although the prognosis is serious, this is no worse during the acute phase, than of the first-ever non-traumatic intracerebral hemorrhages. Clinical profiles were different in recurrent non-traumatic intracerebral hemorrhage patients when compared to first-ever non-traumatic intracerebral hemorrhage patients. (c) 2012 Elsevier Espana, S.L. All rights reserved.
引用
收藏
页码:538 / 541
页数:4
相关论文
共 20 条
[1]  
[Anonymous], 2011, GUIES MED DIAGN TRAC, P159
[2]   Predictive clinical factors of in-hospital mortality in 231 consecutive patients with cardioembolic cerebral infarction [J].
Arboix, A ;
García-Eroles, L ;
Massons, J ;
Oliveres, M .
CEREBROVASCULAR DISEASES, 1998, 8 (01) :8-13
[3]   Lacunar infarcts in patients aged 85 years and older [J].
Arboix, A ;
García-Eroles, L ;
Massons, J ;
Oliveres, M ;
Targa, C .
ACTA NEUROLOGICA SCANDINAVICA, 2000, 101 (01) :25-29
[4]   Recurrent lacunar infarction following a previous lacunar stroke: a clinical study of 122 patients [J].
Arboix, A. ;
Font, A. ;
Garro, C. ;
Garcia-Eroles, L. ;
Comes, E. ;
Massons, J. .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2007, 78 (12) :1392-1394
[5]   Clinical features and functional outcome of intracerebral hemorrhage in patients aged 85 and older [J].
Arboix, A ;
Vall-Llosera, A ;
García-Eroles, L ;
Massons, J ;
Oliveres, M ;
Targa, C .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2002, 50 (03) :449-454
[6]   Site of bleeding and early outcome in primary intracerebral hemorrhage [J].
Arboix, A ;
Comes, E ;
García-Eroles, L ;
Massons, J ;
Oliveres, M ;
Balcells, M ;
Targa, C .
ACTA NEUROLOGICA SCANDINAVICA, 2002, 105 (04) :282-288
[7]   Hemorrhagic lacunar stroke [J].
Arboix, A ;
García-Eroles, L ;
Massons, J ;
Oliveres, M ;
Targa, C .
CEREBROVASCULAR DISEASES, 2000, 10 (03) :229-234
[8]   Trends in Risk Factors, Stroke Subtypes and Outcome [J].
Arboix, Adria ;
Cendros, Victoria ;
Besa, Marta ;
Garcia-Eroles, Luis ;
Oliveres, Montserrat ;
Targa, Cecilia ;
Balcells, Miquel ;
Comes, Emili ;
Massons, Joan .
CEREBROVASCULAR DISEASES, 2008, 26 (05) :509-516
[9]   Recurrent ischemic stroke. Study of 605 patients [J].
Arboix, Adria ;
Massons, Joan ;
Garcia-Eroles, Luis ;
Comes, Emili ;
Balcells, Miquel ;
Oliveres, Montserrat .
MEDICINA CLINICA, 2011, 137 (12) :541-545
[10]   Aspirin and recurrent intracerebral hemorrhage in cerebral amyloid angiopathy [J].
Biffi, A. ;
Halpin, A. ;
Towfighi, A. ;
Gilson, A. ;
Busl, K. ;
Rost, N. ;
Smith, E. E. ;
Greenberg, M. S. ;
Rosand, J. ;
Viswanathan, A. .
NEUROLOGY, 2010, 75 (08) :693-698