Genetic epidemiology of congenital muscular dystrophy in a sample from north-east Italy

被引：78

作者：

Mostacciuolo, ML ^{[1
]}

Miorin, M ^{[1
]}

Martinello, F ^{[1
]}

Angelini, C ^{[1
]}

Perini, P ^{[1
]}

Trevisan, CP ^{[1
]}

机构：

[1] UNIV PADUA,IST CLIN MALATTIE NERVOSE & MENTALI,I-35128 PADUA,ITALY

来源：

HUMAN GENETICS | 1996年 / 97卷 / 03期

关键词：

D O I：

10.1007/BF02185752

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Congenital muscular dystrophy (CMD) is a heterogenous disease with autosomic recessive transmission. In an epidemiological study in four provinces of Veneto (region of 2586830 inhabitants in north-east Italy), the recorded incidence rate for the period 1979-1993 was 4.65 x 10(-5); the prevalence rate in the year 1993 was 6.8 x 10(-6). The incidence and the prevalence rates that we have obtained during the course of our investigation represent the first estimates for CMD in Europe and show that this myopathy is among the most frequent neuromuscular diseases with autosomic recessive transmission.

引用

页码：277 / 279

页数：3

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