Necrotizing Soft Tissue Infections

被引:25
作者
Hussein, Qaali A. [1 ]
Anaya, Daniel A. [1 ,2 ,3 ]
机构
[1] Baylor Coll Med, Michael E DeBakey Dept Surg, Houston, TX 77030 USA
[2] Michael E DeBakey VA Med Ctr, Houston, TX 77030 USA
[3] Michael E DeBakey VA Med Ctr, Houston Vet Affairs Hlth Serv Res & Dev Ctr Excel, Houston, TX 77030 USA
关键词
Necrotizing soft tissue infections; NSTI; Necrotizing fasciitis; Gangrene; Clostridial infection; Group A streptococcal infection; LABORATORY RISK INDICATOR; TOXIC-SHOCK-SYNDROME; HYPERBARIC-OXYGEN; EARLY RECOGNITION; FASCIITIS; MORTALITY; MANAGEMENT; THERAPY; IMMUNOGLOBULIN; DETERMINANTS;
D O I
10.1016/j.ccc.2013.06.001
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Necrotizing soft tissue infections (NSTIs) are infrequent yet highly lethal infections, and a high index of suspicion is required for early diagnosis. Diagnosing NSTIs early can be challenging, and knowledge of the available tools is essential to provide appropriate treatment. The mainstay of treatment is early and complete, surgical debridement combined with antimicrobial therapy, close monitoring with further debridement as needed, and physiologic support. Mortality continues to be high, and delayed surgical treatment is the most important risk factor. For the long-term recovery of patients with NSTI, providing early physiologic and nutritional support and physical rehabilitation is essential.
引用
收藏
页码:795 / +
页数:13
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