Surgery and Hepatocellular Carcinoma

被引:51
作者
Akamatsu, Nobuhisa [1 ]
Cillo, Umberto [2 ]
Cucchetti, Alessandro [3 ,4 ,5 ]
Donadon, Matteo [6 ,7 ]
Pinna, Antonio Daniele [3 ,4 ,5 ]
Torzilli, Guido [6 ,7 ]
Kokudo, Norihiro [1 ]
机构
[1] Univ Tokyo, Grad Sch Med, Hepatobiliary Pancreat Surg Div, Dept Surg,Artificial Organ & Organ Transplantat D, Tokyo, Japan
[2] Univ Padua, Unita Chirurg Epatobiliare & Trapianto Epat, Azienda Osped, Padua, Italy
[3] Univ Bologna, DIMEC, Dept Med & Surg Sci, Bologna, Italy
[4] Univ Bologna, S Orsola Malpighi Hosp, Bologna, Italy
[5] Univ Bologna, Alma Mater Studiorum, Bologna, Italy
[6] Humanitas Univ, Div Hepatobiliary & Gen Surg, Dept Surg, Milan, Italy
[7] Humanitas Res Hosp, Milan, Italy
关键词
Hepatocellular carcinoma; Liver resection; Liver transplantation; DONOR LIVER-TRANSPLANTATION; DISEASE MELD SCORE; EASL/AASLD RECOMMENDATIONS; HEPATIC RESECTION; SURVIVAL BENEFIT; STAGING SYSTEM; LIVING-DONOR; CANDIDATES; ALLOCATION; HEPATECTOMY;
D O I
10.1159/000449344
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The optimal surgical strategy for hepatocellular carcinoma (HCC) is under active debate. Biomarkers of the liver functional reserve as well as volumetric analysis of the future liver remnant are essential for safe liver resection of HCC. The present algorithms applied to surgical strategies for HCC are not ideal because many patients who could potentially undergo safe resection are deemed liver transplant candidates in Western countries, whereas the opposite is the case in Eastern countries. In addition, there is too much focus on expanded criteria for patients with HCC to undergo liver transplantation. The transplantation benefit for patients with HCC should be considered based not only on the individual's benefit, but also on the effect of other patients waiting for LT for other indications. Copyright (C) 2016 S. Karger AG, Basel
引用
收藏
页码:44 / 50
页数:7
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