Neuromodulation for fecal incontinence: An effective surgical intervention

被引:18
作者
Chiarioni, Giuseppe [1 ,2 ,3 ]
Palsson, Olafur S. [2 ,3 ]
Asteria, Corrado R. [4 ]
Whitehead, William E. [2 ,3 ]
机构
[1] Univ Verona, Div Gastroenterol, Azienda Osped Univ Integrata Verona, Valeggio S M Hosp, I-37067 Verona, Italy
[2] Univ N Carolina, Div Gastroenterol & Hepatol, Chapel Hill, NC 27516 USA
[3] Univ N Carolina, Ctr Funct Gastrointestinal & Motil Disorders, Chapel Hill, NC 27516 USA
[4] Asola Gen Hosp, Dept Surg & Orthoped, Gen Surg Unit, I-46041 Asola, Mantova, Italy
关键词
Fecal incontinence; Neuromodulation; Sacral nerve stimulation; Biofeedback; Anal sphincter; SACRAL NERVE-STIMULATION; URINARY-INCONTINENCE; COST-EFFECTIVENESS; ANAL-SPHINCTER; INSTITUTION; BIOFEEDBACK; EXPERIENCE; EFFICACY; THERAPY;
D O I
10.3748/wjg.v19.i41.7048
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Fecal incontinence is a disabling symptom with medical and social implications, including fear, embarrassment, isolation and even depression. Most patients live in seclusion and have to plan their life around the symptom, with secondary impairment of their quality of life. Conservative management and biofeedback therapy are reported to benefit a good percentage of those affected. However, surgery must be considered in the non-responder population. Recently, sacral nerve electrostimulation, lately named neuromodulation, has been reported to benefit patients with fecal incontinence in randomized controlled trials more than placebo stimulation and conservative management, by some unknown mechanism. Neuromodulation is a minimally invasive procedure with a low rate of adverse events and apparently favorable cost-efficacy profile. This review is intended to expand knowledge about this effective intervention among the non-surgically skilled community who deals with this disabled group of patients. (C) 2013 Baishideng Publishing Group Co., Limited. All rights reserved.
引用
收藏
页码:7048 / 7054
页数:7
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